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- W2560580431 abstract "Pevonedistat (MLN-4924, TAK-924) is a first-in-class inhibitor of Nedd-8 activating enzyme (NAE) currently undergoing clinical evaluation in oncology. This chapter will discuss the identification of pevonedistat and describe the synthetic routes undertaken by discovery chemists to provide material for pre-clinical studies." @default.
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- W2560580431 date "2016-01-01" @default.
- W2560580431 modified "2023-10-10" @default.
- W2560580431 title "Synthesis of a Potent NAE Inhibitor: Pevonedistat" @default.
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- W2560580431 doi "https://doi.org/10.1021/bk-2016-1240.ch001" @default.
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