FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2560641472> ?p ?o ?g. }

• W2560641472 abstract "Abstract Title: Feasibility and Tolerability of Quantitative Sensory Testing in Patients with Sickle Cell Disease at the End of a Vasocclusive Episode Background: Children with Sickle Cell Disease (SCD) have increased sensitivity to heat and cold pain (Brandow et al) during steady state. It is unknown if sensitivity to pain varies with a Vaso-Occlusive Episode (VOE).Characterization of pain sensitivity during acute VOE is essential to the understanding of the transition to chronic pain. While the administration of pain stimuli associated with QST during a VOE is obviously untenable, it is unknown if patients will tolerate QST procedures at the end of a VOE. Aim: To determine feasibility and tolerability of QST procedures at the end of VOE. Methods: Patients with SCD were offered quantitative sensory testing (QST) at steady state (at least 2 weeks following a VOE) and prior to or following discharge from the hospital for a VOE-related admission. Patients were contacted during hospitalization for VOE and timing of QST was determined by patient preference and taking into account readiness for discharge from the hospital. QST procedures included estimation of pressure, mechanical and thermal pain thresholds and tolerance (excluding cold tolerance) as well as windup values. At each time point, participants completed the PROMIS measures of pain intensity, pain interference, anxiety, depressive symptoms, sleep, fatigue and peer relationships. Participants also completed the Pain Catastrophizing Scale ((PCS)-Sullivan et al), Child Somatization Inventory (Walker et al), Pain Coping Inventory (Varni et al)* as well as Peds QL Generic and SCD specific measures of Quality of life*. After the QST procedures, participants completed the Gracely box scales (0-20 scale rating pain unpleasantness/intensity). Results: Ten patients who had an episode of VOE during the study period underwent QST at a median of 3.8 days after admission. The median age of participants who underwent testing was 16.5 years (IQR 11-20). 6 of 10 patients were female. Sixteen patients in VOE were offered QST testing. Eight of 12 patients who had undergone QST testing at steady state and 2 of 4 patients who had not previously undergone QST testing consented to QST testing. Nine patients completed testing at both steady state and following a VOE. Thermal testing was well tolerated by all participants (n=1 not offered due to equipment unavailability). Mechanical pain testing/windup was partially omitted (n=1) by patient request. The median Gracely Box Scale (0-20) score following QST was 0.5 (IQR 0-4, range 0-6) for pain unpleasantness and was 0 (IQR 0-6, range 0-8) for pain intensity. Conclusions: Quantitative Sensory Testing is well accepted, feasible and well tolerated in patients with SCD at the end of a Vasoocclusive Episode. Acknowledgments: 1- ASH Clinical Research Training Institute 2- Sickle Cell Disease Association of America 3- *PedsQL™ contact information and permission to use: Mapi Research Trust, Lyon, France. E-mail: PROinformation@mapi-trust.org – Internet: www.Mapi-trust.org and http://www.pedsql.org/index.html Disclosures No relevant conflicts of interest to declare." @default.
• W2560641472 created "2016-12-16" @default.
• W2560641472 creator A5002294162 @default.
• W2560641472 creator A5036837911 @default.
• W2560641472 creator A5048597717 @default.
• W2560641472 creator A5072101808 @default.
• W2560641472 date "2014-12-06" @default.
• W2560641472 modified "2023-09-27" @default.
• W2560641472 title "Feasibility and Tolerability of Quantitative Sensory Testing in Patients with Sickle Cell Disease at the End of a Vasoocclusive Episode" @default.
• W2560641472 doi "https://doi.org/10.1182/blood.v124.21.3519.3519" @default.
• W2560641472 hasPublicationYear "2014" @default.
• W2560641472 type Work @default.
• W2560641472 sameAs 2560641472 @default.
• W2560641472 citedByCount "0" @default.
• W2560641472 crossrefType "journal-article" @default.
• W2560641472 hasAuthorship W2560641472A5002294162 @default.
• W2560641472 hasAuthorship W2560641472A5036837911 @default.
• W2560641472 hasAuthorship W2560641472A5048597717 @default.
• W2560641472 hasAuthorship W2560641472A5072101808 @default.
• W2560641472 hasConcept C118552586 @default.
• W2560641472 hasConcept C126322002 @default.
• W2560641472 hasConcept C15744967 @default.
• W2560641472 hasConcept C180747234 @default.
• W2560641472 hasConcept C1862650 @default.
• W2560641472 hasConcept C197934379 @default.
• W2560641472 hasConcept C2777631960 @default.
• W2560641472 hasConcept C2778375690 @default.
• W2560641472 hasConcept C2778620579 @default.
• W2560641472 hasConcept C2779134260 @default.
• W2560641472 hasConcept C2780441568 @default.
• W2560641472 hasConcept C2781118164 @default.
• W2560641472 hasConcept C2909026353 @default.
• W2560641472 hasConcept C42219234 @default.
• W2560641472 hasConcept C558461103 @default.
• W2560641472 hasConcept C71924100 @default.
• W2560641472 hasConcept C94487597 @default.
• W2560641472 hasConceptScore W2560641472C118552586 @default.
• W2560641472 hasConceptScore W2560641472C126322002 @default.
• W2560641472 hasConceptScore W2560641472C15744967 @default.
• W2560641472 hasConceptScore W2560641472C180747234 @default.
• W2560641472 hasConceptScore W2560641472C1862650 @default.
• W2560641472 hasConceptScore W2560641472C197934379 @default.
• W2560641472 hasConceptScore W2560641472C2777631960 @default.
• W2560641472 hasConceptScore W2560641472C2778375690 @default.
• W2560641472 hasConceptScore W2560641472C2778620579 @default.
• W2560641472 hasConceptScore W2560641472C2779134260 @default.
• W2560641472 hasConceptScore W2560641472C2780441568 @default.
• W2560641472 hasConceptScore W2560641472C2781118164 @default.
• W2560641472 hasConceptScore W2560641472C2909026353 @default.
• W2560641472 hasConceptScore W2560641472C42219234 @default.
• W2560641472 hasConceptScore W2560641472C558461103 @default.
• W2560641472 hasConceptScore W2560641472C71924100 @default.
• W2560641472 hasConceptScore W2560641472C94487597 @default.
• W2560641472 hasLocation W25606414721 @default.
• W2560641472 hasOpenAccess W2560641472 @default.
• W2560641472 hasPrimaryLocation W25606414721 @default.
• W2560641472 hasRelatedWork W1572578205 @default.
• W2560641472 hasRelatedWork W2040868891 @default.
• W2560641472 hasRelatedWork W2081136959 @default.
• W2560641472 hasRelatedWork W2083571532 @default.
• W2560641472 hasRelatedWork W2085698204 @default.
• W2560641472 hasRelatedWork W2140368741 @default.
• W2560641472 hasRelatedWork W2399926514 @default.
• W2560641472 hasRelatedWork W24498639 @default.
• W2560641472 hasRelatedWork W2737004030 @default.
• W2560641472 hasRelatedWork W2792684034 @default.
• W2560641472 hasRelatedWork W2972223498 @default.
• W2560641472 hasRelatedWork W2996031160 @default.
• W2560641472 hasRelatedWork W2996839702 @default.
• W2560641472 hasRelatedWork W3027398985 @default.
• W2560641472 hasRelatedWork W3111247060 @default.
• W2560641472 hasRelatedWork W3132354253 @default.
• W2560641472 hasRelatedWork W3211255584 @default.
• W2560641472 hasRelatedWork W3213311288 @default.
• W2560641472 hasRelatedWork W79648401 @default.
• W2560641472 hasRelatedWork W2509610332 @default.
• W2560641472 isParatext "false" @default.
• W2560641472 isRetracted "false" @default.
• W2560641472 magId "2560641472" @default.
• W2560641472 workType "article" @default.