FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2560702975> ?p ?o ?g. }

• W2560702975 endingPage "e141" @default.
• W2560702975 startingPage "e135" @default.
• W2560702975 abstract "Purpose of the Report Peptide receptor radionuclide therapy (PRRT) is an effective treatment for advanced neuroendocrine tumors (NET); however, long-term survival data are scarce. The aim of this study is to determine long-term survival in patients with metastatic midgut NET, according to response to PRRT. Patients and Methods One hundred thirty-three consecutive patients with progressive metastatic midgut NET underwent PRRT. Response at 1 year post PRRT was classified as partial response, stable disease, disease progression, or death. Survival was assessed according to response to PRRT, and predictors of overall survival (OS) and progression-free survival (PFS) were identified. Results At 1 year post PRRT, 9% had partial response, 50.4% stable disease, 10.5% disease progression, and 30.1% were dead. The OS was 33.5, and PFS was 28.5 months. Predictors of disease progression/death were chromogranin A greater than 10 ULN (OR, 4.6; P = 0.007) and hepatic tumor load greater than 50% (OR, 5; P = 0.004). There was no difference in OS between patients with partial response and those with stable disease post PRRT. In multivariate Cox regression, predictors of OS were number of PRRT cycles (HR, 0.33; P < 0.0005), hepatic tumor load greater than 50% (HR, 3.46; P = 0.01), and outcome at 1 year post PRRT (HR, 21.37; P < 0.0005). Predictors of PFS were number of PRRT cycles (HR, 0.39; P < 0.0005), previous resection of liver metastases (HR, 3.56; P = 0,023), and hepatic tumor load greater than 50% (HR, 3.06; P < 0.0005). Conclusions Patients with progressive metastatic midgut NET who achieved stable disease at 1 year post PRRT had similar OS with those with partial response. Hepatic tumor burden was a strong predictor of response to PRRT, PFS, and OS." @default.
• W2560702975 created "2016-12-16" @default.
• W2560702975 creator A5003310393 @default.
• W2560702975 creator A5010371525 @default.
• W2560702975 creator A5026573275 @default.
• W2560702975 creator A5031563853 @default.
• W2560702975 creator A5042769402 @default.
• W2560702975 creator A5043082949 @default.
• W2560702975 creator A5051215504 @default.
• W2560702975 creator A5078176163 @default.
• W2560702975 creator A5089389627 @default.
• W2560702975 date "2017-03-01" @default.
• W2560702975 modified "2023-09-26" @default.
• W2560702975 title "The Impact of Radiological Response to Peptide Receptor Radionuclide Therapy on Overall Survival in Patients With Metastatic Midgut Neuroendocrine Tumors" @default.
• W2560702975 cites W1992543080 @default.
• W2560702975 cites W2006821285 @default.
• W2560702975 cites W2011732158 @default.
• W2560702975 cites W2014971874 @default.
• W2560702975 cites W2018913523 @default.
• W2560702975 cites W2036154071 @default.
• W2560702975 cites W2063178653 @default.
• W2560702975 cites W2074731710 @default.
• W2560702975 cites W2079633798 @default.
• W2560702975 cites W2090257199 @default.
• W2560702975 cites W2092706522 @default.
• W2560702975 cites W2098482546 @default.
• W2560702975 cites W2099933501 @default.
• W2560702975 cites W2102617530 @default.
• W2560702975 cites W2107276199 @default.
• W2560702975 cites W2115686439 @default.
• W2560702975 cites W2124077899 @default.
• W2560702975 cites W2125398839 @default.
• W2560702975 cites W2128267006 @default.
• W2560702975 cites W2133090399 @default.
• W2560702975 cites W2137385634 @default.
• W2560702975 cites W2145243099 @default.
• W2560702975 cites W2149214723 @default.
• W2560702975 cites W2150478512 @default.
• W2560702975 cites W2157320520 @default.
• W2560702975 cites W2158474413 @default.
• W2560702975 cites W2160327982 @default.
• W2560702975 cites W2164614522 @default.
• W2560702975 doi "https://doi.org/10.1097/rlu.0000000000001457" @default.
• W2560702975 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/27922860" @default.
• W2560702975 hasPublicationYear "2017" @default.
• W2560702975 type Work @default.
• W2560702975 sameAs 2560702975 @default.
• W2560702975 citedByCount "12" @default.
• W2560702975 countsByYear W25607029752017 @default.
• W2560702975 countsByYear W25607029752018 @default.
• W2560702975 countsByYear W25607029752019 @default.
• W2560702975 countsByYear W25607029752020 @default.
• W2560702975 countsByYear W25607029752021 @default.
• W2560702975 countsByYear W25607029752022 @default.
• W2560702975 countsByYear W25607029752023 @default.
• W2560702975 crossrefType "journal-article" @default.
• W2560702975 hasAuthorship W2560702975A5003310393 @default.
• W2560702975 hasAuthorship W2560702975A5010371525 @default.
• W2560702975 hasAuthorship W2560702975A5026573275 @default.
• W2560702975 hasAuthorship W2560702975A5031563853 @default.
• W2560702975 hasAuthorship W2560702975A5042769402 @default.
• W2560702975 hasAuthorship W2560702975A5043082949 @default.
• W2560702975 hasAuthorship W2560702975A5051215504 @default.
• W2560702975 hasAuthorship W2560702975A5078176163 @default.
• W2560702975 hasAuthorship W2560702975A5089389627 @default.
• W2560702975 hasConcept C126322002 @default.
• W2560702975 hasConcept C143998085 @default.
• W2560702975 hasConcept C170493617 @default.
• W2560702975 hasConcept C204232928 @default.
• W2560702975 hasConcept C2778822529 @default.
• W2560702975 hasConcept C2779066768 @default.
• W2560702975 hasConcept C2779134260 @default.
• W2560702975 hasConcept C2993559085 @default.
• W2560702975 hasConcept C3017732841 @default.
• W2560702975 hasConcept C50382708 @default.
• W2560702975 hasConcept C71924100 @default.
• W2560702975 hasConcept C77231918 @default.
• W2560702975 hasConcept C90924648 @default.
• W2560702975 hasConceptScore W2560702975C126322002 @default.
• W2560702975 hasConceptScore W2560702975C143998085 @default.
• W2560702975 hasConceptScore W2560702975C170493617 @default.
• W2560702975 hasConceptScore W2560702975C204232928 @default.
• W2560702975 hasConceptScore W2560702975C2778822529 @default.
• W2560702975 hasConceptScore W2560702975C2779066768 @default.
• W2560702975 hasConceptScore W2560702975C2779134260 @default.
• W2560702975 hasConceptScore W2560702975C2993559085 @default.
• W2560702975 hasConceptScore W2560702975C3017732841 @default.
• W2560702975 hasConceptScore W2560702975C50382708 @default.
• W2560702975 hasConceptScore W2560702975C71924100 @default.
• W2560702975 hasConceptScore W2560702975C77231918 @default.
• W2560702975 hasConceptScore W2560702975C90924648 @default.
• W2560702975 hasIssue "3" @default.
• W2560702975 hasLocation W25607029751 @default.
• W2560702975 hasLocation W25607029752 @default.
• W2560702975 hasOpenAccess W2560702975 @default.
• W2560702975 hasPrimaryLocation W25607029751 @default.
• W2560702975 hasRelatedWork W1970326135 @default.
• W2560702975 hasRelatedWork W2533458501 @default.

• next