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• W2560757989 abstract "The localizations of nonheme‑Fe (III) and Fe (II) were studied in the hypothalamo‑neurohypophyseal system of the rat brain by light and electron microscopic nonheme iron‑histochemistry. Fe (III) ‑deposit was heavily accumulated in the parvocellular part of the hypothalamic paraventricular nucleus (HPV) where numerous glias were stained. Fe (III) ‑deposit heavily fi lled the cytosol and lysosomes of microglia‑ oligodendrocyte‑ and astrocyte‑like cells while neurons contained only a small number of Fe (III) ‑laden lysosomes. Fine processes of Fe (III) ‑ laden microglia‑ and oligodendrocyte‑like cells closely ensheathed the cell body and proximal dendrites of neurons. Fe (III) ‑laden astrocyte‑ like cells tightly enclosed the capillary wall. The magnocellular part of the HPV and the supraoptic nucleus were less intensely stained than the parvocellular part of the HPV. The secretory axon terminals in the outer lamina of the median eminence (ME) and the posterior pituitary including the Herring bodies contained Fe (III) ‑laden small lysosomes among densely aggregated secretory granules. The secretory axon terminals in the ME were tightly enclosed by heavily Fe (III) ‑laden processes of tanycyte. The heavily Fe (III) ‑laden pituicytes and interstitial pericapillary phagocytes closely approached the secretory axon terminals in the posterior pituitary. Fe (II) was largely localized in the lysosomes throughout the hypothalamo‑neurohypophyseal system." @default.
• W2560757989 created "2016-12-16" @default.
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• W2560757989 date "2009-03-31" @default.
• W2560757989 modified "2023-09-23" @default.
• W2560757989 title "Nonheme-Iron Deposition in the Hypothalamo-Neurohypophyseal System of the Rat Brain" @default.
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