Matches in SemOpenAlex for { <https://semopenalex.org/work/W2560794920> ?p ?o ?g. }
- W2560794920 endingPage "517" @default.
- W2560794920 startingPage "508" @default.
- W2560794920 abstract "The aim of this study was to evaluate the effects of oxygen consumption-matched short-term interval walking training (IWT) vs continuous walking training (CWT) on glycaemic control, including glycaemic variability, in individuals with type 2 diabetes. We also assessed whether any training-induced improvements in glycaemic control were associated with systemic oxidative stress levels. Participants (n = 14) with type 2 diabetes completed a crossover trial using three interventions (control intervention [CON], CWT and IWT), each lasting 2 weeks. These were performed in a randomised order (computerised generated randomisation) and separated by washout periods of 4 or 8 weeks after CON or training interventions, respectively. Training included ten supervised treadmill sessions, lasting 60 min/session, and was performed at the research facility. CWT was performed at moderate walking speed (75.6% ± 2.5% of walking peak oxygen consumption [ $$ overset{.}{V}{mathrm{O}}_{2mathrm{peak}} $$ ]), while IWT was performed as alternating 3 min repetitions at slow (58.9% ± 2.0% $$ overset{.}{V}{mathrm{O}}_{2mathrm{peak}} $$ ) and fast (90.0% ± 3.6% $$ overset{.}{V}{mathrm{O}}_{2mathrm{peak}} $$ ) walking speed. Before and after each intervention, the following was assessed: 24 h continuous glucose monitoring (CGM) and urinary free 8-iso prostaglandin F2α (8-iso PGF2α; a marker for oxidative stress), physical fitness and body composition. Neither participants nor assessors were blinded to the interventions. No intervention-induced changes were seen in physical fitness or body composition. Compared with baseline, IWT reduced mean glucose levels non-significantly (−0.7 ± 0.3 mmol/l, p = 0.08) and significantly reduced maximum glucose levels (−1.8 ± 0.5 mmol/l, p = 0.04) and mean amplitude of glycaemic excursions (MAGE; −1.7 ± 0.4 mmol/l, p = 0.02), whereas no significant within-group changes were seen with CON or CWT. Although 8-iso PGF2α was associated with minimum glucose levels at baseline, no change in 8-iso PGF2α was seen with any intervention, nor were there any associations between changes in 8-iso PGF2α and changes in glycaemic control (p > 0.05 for all). No adverse effects were observed with any of the interventions. Short-term IWT, but not CWT, improves CGM-derived measures of glycaemic control independent of changes in physical fitness and body composition in individuals with type 2 diabetes. Systemic oxidative stress levels are unaffected by short-term walking and changes in oxidative stress levels are not associated with changes in glycaemic control. ClinicalTrials.gov NCT02320526 The Centre for Physical Activity Research (CFAS) is supported by a grant from TrygFonden. During the study period, the Centre of Inflammation and Metabolism (CIM) was supported by a grant from the Danish National Research Foundation (DNRF55). The study was further supported by grants from Diabetesforeningen, Augustinusfonden and Krista og Viggo Petersens Fond. CIM/CFAS is a member of the Danish Center for Strategic Research in Type 2 Diabetes (DD2; the Danish Council for Strategic Research, grant no. 09-067009 and 09-075724). MR-L was supported by a post-doctoral grant from the Danish Diabetes Academy supported by the Novo Nordisk Foundation." @default.
- W2560794920 created "2016-12-16" @default.
- W2560794920 creator A5026691599 @default.
- W2560794920 creator A5033826448 @default.
- W2560794920 creator A5048868544 @default.
- W2560794920 creator A5051857476 @default.
- W2560794920 creator A5058503252 @default.
- W2560794920 creator A5059817069 @default.
- W2560794920 creator A5074362044 @default.
- W2560794920 date "2016-12-09" @default.
- W2560794920 modified "2023-10-13" @default.
- W2560794920 title "The effects of 2 weeks of interval vs continuous walking training on glycaemic control and whole-body oxidative stress in individuals with type 2 diabetes: a controlled, randomised, crossover trial" @default.
- W2560794920 cites W1556618881 @default.
- W2560794920 cites W1851758680 @default.
- W2560794920 cites W1871468534 @default.
- W2560794920 cites W1967265218 @default.
- W2560794920 cites W1978884916 @default.
- W2560794920 cites W1987588766 @default.
- W2560794920 cites W2004008756 @default.
- W2560794920 cites W2008564665 @default.
- W2560794920 cites W2021448591 @default.
- W2560794920 cites W2025870581 @default.
- W2560794920 cites W2030199901 @default.
- W2560794920 cites W2039854830 @default.
- W2560794920 cites W2063298884 @default.
- W2560794920 cites W2071997139 @default.
- W2560794920 cites W2088224247 @default.
- W2560794920 cites W2096409056 @default.
- W2560794920 cites W2101741459 @default.
- W2560794920 cites W2103227592 @default.
- W2560794920 cites W2104498985 @default.
- W2560794920 cites W2105731956 @default.
- W2560794920 cites W2105824687 @default.
- W2560794920 cites W2106384285 @default.
- W2560794920 cites W2107614741 @default.
- W2560794920 cites W2109416725 @default.
- W2560794920 cites W2118261488 @default.
- W2560794920 cites W2120175636 @default.
- W2560794920 cites W2123946565 @default.
- W2560794920 cites W2127238518 @default.
- W2560794920 cites W2134334767 @default.
- W2560794920 cites W2137206121 @default.
- W2560794920 cites W2145562665 @default.
- W2560794920 cites W2149778174 @default.
- W2560794920 cites W2150144569 @default.
- W2560794920 cites W2150879111 @default.
- W2560794920 cites W2158620938 @default.
- W2560794920 cites W2159086743 @default.
- W2560794920 cites W2167851640 @default.
- W2560794920 cites W2176427838 @default.
- W2560794920 cites W2177834950 @default.
- W2560794920 cites W2183649177 @default.
- W2560794920 cites W2411741394 @default.
- W2560794920 cites W3171237122 @default.
- W2560794920 doi "https://doi.org/10.1007/s00125-016-4170-6" @default.
- W2560794920 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/27942800" @default.
- W2560794920 hasPublicationYear "2016" @default.
- W2560794920 type Work @default.
- W2560794920 sameAs 2560794920 @default.
- W2560794920 citedByCount "41" @default.
- W2560794920 countsByYear W25607949202017 @default.
- W2560794920 countsByYear W25607949202018 @default.
- W2560794920 countsByYear W25607949202019 @default.
- W2560794920 countsByYear W25607949202020 @default.
- W2560794920 countsByYear W25607949202021 @default.
- W2560794920 countsByYear W25607949202022 @default.
- W2560794920 countsByYear W25607949202023 @default.
- W2560794920 crossrefType "journal-article" @default.
- W2560794920 hasAuthorship W2560794920A5026691599 @default.
- W2560794920 hasAuthorship W2560794920A5033826448 @default.
- W2560794920 hasAuthorship W2560794920A5048868544 @default.
- W2560794920 hasAuthorship W2560794920A5051857476 @default.
- W2560794920 hasAuthorship W2560794920A5058503252 @default.
- W2560794920 hasAuthorship W2560794920A5059817069 @default.
- W2560794920 hasAuthorship W2560794920A5074362044 @default.
- W2560794920 hasBestOaLocation W25607949201 @default.
- W2560794920 hasConcept C126322002 @default.
- W2560794920 hasConcept C134018914 @default.
- W2560794920 hasConcept C142724271 @default.
- W2560794920 hasConcept C168563851 @default.
- W2560794920 hasConcept C1862650 @default.
- W2560794920 hasConcept C196310339 @default.
- W2560794920 hasConcept C204787440 @default.
- W2560794920 hasConcept C27081682 @default.
- W2560794920 hasConcept C2776151105 @default.
- W2560794920 hasConcept C2777180221 @default.
- W2560794920 hasConcept C2777953023 @default.
- W2560794920 hasConcept C2777973682 @default.
- W2560794920 hasConcept C555293320 @default.
- W2560794920 hasConcept C71924100 @default.
- W2560794920 hasConcept C84393581 @default.
- W2560794920 hasConcept C87813604 @default.
- W2560794920 hasConceptScore W2560794920C126322002 @default.
- W2560794920 hasConceptScore W2560794920C134018914 @default.
- W2560794920 hasConceptScore W2560794920C142724271 @default.
- W2560794920 hasConceptScore W2560794920C168563851 @default.
- W2560794920 hasConceptScore W2560794920C1862650 @default.
- W2560794920 hasConceptScore W2560794920C196310339 @default.