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- W2560804919 abstract "During gestation and lactation in mammals, calcium and other minerals are transferred from female to offspring to support skeletal ossification. To meet mineral requirements, females commonly mobilize mineral from their own skeleton to augment dietary intake. Because the fitness costs of bone loss are expected to limit the amount of endogenous mineral that females transfer to their young, the amount of mineral allocated to offspring is predicted to be influenced by the availability of mineral in the female's diet. Calcium is the most abundant element in bone, and exogenous calcium appears to be limiting for many species. Thus, we expected that females would adjust mineral allocation to offspring relative to calcium abundance in the diet. We provided breeding female white-footed mice (Peromyscus leucopus) with a low-calcium (0.1% Ca) or a standard diet (0.85% Ca) for approximately 1 year. Body mass and skeletal size of pups did not differ between diets. Relative to pups from females on the standard diet, pups from females on the low-calcium diet had less calcium and phosphorus in their femurs and humeri, less body calcium content, reduced mass of their femurs and humeri, and had femurs with a reduced width. Reproducing white-footed mice mobilize more bone when calcium intake is low; however, our results suggest that this does not completely compensate for a reduction in calcium intake. Thus, it appears that when calcium availability is low, female white-footed mice reduce the quantity of mineral allocated per offspring as a means of maintaining their own skeletal condition." @default.
- W2560804919 created "2016-12-16" @default.
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- W2560804919 date "2016-11-01" @default.
- W2560804919 modified "2023-10-17" @default.
- W2560804919 title "Female White-Footed Mice (<i>Peromyscus leucopus</i>) Trade Off Offspring Skeletal Quality for Self-Maintenance When Dietary Calcium Intake is Low" @default.
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- W2560804919 doi "https://doi.org/10.1002/jez.2051" @default.
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