FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2560809684> ?p ?o ?g. }

• W2560809684 endingPage "251" @default.
• W2560809684 startingPage "247" @default.
• W2560809684 abstract "Bacterial biofilms are surface-attached communities of slow-growing or non-replicating bacteria tolerant to conventional antibiotic therapies. Although biofilms are known to occur in ca. 80% of all bacterial infections, no therapeutic agent has been developed to eradicate bacteria housed within biofilms. We have discovered that nitroxoline, an antibacterial agent used to treat urinary tract infections, displays broad-spectrum biofilm-eradicating activities against major human pathogens, including drug-resistant Staphylococcus aureus and Acinetobacter baumannii strains. In this study, the effectiveness of nitroxoline to eradicate biofilms was determined using an in vitro [minimum biofilm eradication concentration (MBEC) = 46.9 µM against A. baumannii] and ex vivo porcine skin model (2-3 log reduction in viable biofilm cells). Nitroxoline was also found to eradicate methicillin-resistant S. aureus (MRSA) persister cells in non-biofilm (stationary) cultures, whereas vancomycin and daptomycin were found to be inactive. These findings could lead to effective, nitroxoline-based therapies for biofilm-associated infections." @default.
• W2560809684 created "2016-12-16" @default.
• W2560809684 creator A5008352213 @default.
• W2560809684 creator A5048287522 @default.
• W2560809684 creator A5053106621 @default.
• W2560809684 creator A5054855923 @default.
• W2560809684 creator A5057010595 @default.
• W2560809684 creator A5057222593 @default.
• W2560809684 creator A5065597646 @default.
• W2560809684 date "2017-02-01" @default.
• W2560809684 modified "2023-09-25" @default.
• W2560809684 title "Nitroxoline: a broad-spectrum biofilm-eradicating agent against pathogenic bacteria" @default.
• W2560809684 cites W1599551995 @default.
• W2560809684 cites W1931193379 @default.
• W2560809684 cites W1980433906 @default.
• W2560809684 cites W1988874714 @default.
• W2560809684 cites W2001103319 @default.
• W2560809684 cites W2042125375 @default.
• W2560809684 cites W2045825103 @default.
• W2560809684 cites W2062825531 @default.
• W2560809684 cites W2062851027 @default.
• W2560809684 cites W2084413504 @default.
• W2560809684 cites W2100025364 @default.
• W2560809684 cites W2100499697 @default.
• W2560809684 cites W2106351298 @default.
• W2560809684 cites W2127817798 @default.
• W2560809684 cites W2132867380 @default.
• W2560809684 cites W2134536451 @default.
• W2560809684 cites W2175724248 @default.
• W2560809684 cites W2315370795 @default.
• W2560809684 cites W2395434565 @default.
• W2560809684 cites W2418802035 @default.
• W2560809684 cites W2421873954 @default.
• W2560809684 cites W4213353716 @default.
• W2560809684 doi "https://doi.org/10.1016/j.ijantimicag.2016.10.017" @default.
• W2560809684 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/28110918" @default.
• W2560809684 hasPublicationYear "2017" @default.
• W2560809684 type Work @default.
• W2560809684 sameAs 2560809684 @default.
• W2560809684 citedByCount "45" @default.
• W2560809684 countsByYear W25608096842017 @default.
• W2560809684 countsByYear W25608096842018 @default.
• W2560809684 countsByYear W25608096842019 @default.
• W2560809684 countsByYear W25608096842020 @default.
• W2560809684 countsByYear W25608096842021 @default.
• W2560809684 countsByYear W25608096842022 @default.
• W2560809684 countsByYear W25608096842023 @default.
• W2560809684 crossrefType "journal-article" @default.
• W2560809684 hasAuthorship W2560809684A5008352213 @default.
• W2560809684 hasAuthorship W2560809684A5048287522 @default.
• W2560809684 hasAuthorship W2560809684A5053106621 @default.
• W2560809684 hasAuthorship W2560809684A5054855923 @default.
• W2560809684 hasAuthorship W2560809684A5057010595 @default.
• W2560809684 hasAuthorship W2560809684A5057222593 @default.
• W2560809684 hasAuthorship W2560809684A5065597646 @default.
• W2560809684 hasConcept C136622501 @default.
• W2560809684 hasConcept C2776315533 @default.
• W2560809684 hasConcept C2777637488 @default.
• W2560809684 hasConcept C2778651397 @default.
• W2560809684 hasConcept C2778883795 @default.
• W2560809684 hasConcept C2778980435 @default.
• W2560809684 hasConcept C2779489039 @default.
• W2560809684 hasConcept C4937899 @default.
• W2560809684 hasConcept C501593827 @default.
• W2560809684 hasConcept C523546767 @default.
• W2560809684 hasConcept C54355233 @default.
• W2560809684 hasConcept C58123911 @default.
• W2560809684 hasConcept C86803240 @default.
• W2560809684 hasConcept C89423630 @default.
• W2560809684 hasConceptScore W2560809684C136622501 @default.
• W2560809684 hasConceptScore W2560809684C2776315533 @default.
• W2560809684 hasConceptScore W2560809684C2777637488 @default.
• W2560809684 hasConceptScore W2560809684C2778651397 @default.
• W2560809684 hasConceptScore W2560809684C2778883795 @default.
• W2560809684 hasConceptScore W2560809684C2778980435 @default.
• W2560809684 hasConceptScore W2560809684C2779489039 @default.
• W2560809684 hasConceptScore W2560809684C4937899 @default.
• W2560809684 hasConceptScore W2560809684C501593827 @default.
• W2560809684 hasConceptScore W2560809684C523546767 @default.
• W2560809684 hasConceptScore W2560809684C54355233 @default.
• W2560809684 hasConceptScore W2560809684C58123911 @default.
• W2560809684 hasConceptScore W2560809684C86803240 @default.
• W2560809684 hasConceptScore W2560809684C89423630 @default.
• W2560809684 hasFunder F4320332741 @default.
• W2560809684 hasIssue "2" @default.
• W2560809684 hasLocation W25608096841 @default.
• W2560809684 hasLocation W25608096842 @default.
• W2560809684 hasOpenAccess W2560809684 @default.
• W2560809684 hasPrimaryLocation W25608096841 @default.
• W2560809684 hasRelatedWork W1968602861 @default.
• W2560809684 hasRelatedWork W2125076516 @default.
• W2560809684 hasRelatedWork W2406107337 @default.
• W2560809684 hasRelatedWork W2560809684 @default.
• W2560809684 hasRelatedWork W2917569394 @default.
• W2560809684 hasRelatedWork W2997146492 @default.
• W2560809684 hasRelatedWork W3142972077 @default.
• W2560809684 hasRelatedWork W3158218085 @default.
• W2560809684 hasRelatedWork W3178472217 @default.

• next