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- W2560983852 abstract "Executive summaryObjectivesThe aim of this feasibility study was to assess the suitability of CRiiS data to facilitate analysis of treatment outcomes to estimate the effectiveness and cost-effectiveness of Opiate Substitution Therapy (OST) drug types, specifically comparing buprenorphine and methadone, the two main substitute drugs provided, in medically-assisted recovery. SampleThe cohort comprised opiate users newly entering treatment with CRI: defined as those with a triage date on, or after, the date on which CRI commenced service provision. This provided a total cohort of 15 450 clients over the time-period for which data are available, of whom 72% had information about prescribing. Main outcomesThe outcomes considered here were:?planned treatment completion; ?6-month and 12-month re-presentation, post-discharge, to CRI services; ?retention in treatment for 3 months, 6 months and 12 months. ?becoming abstinent; ?ceasing injecting; ?change in days of paid work or education; ?moving into secure housing;?change in self-reported psychological health, physical health and overall quality of life. Outcome analysesAn initial, descriptive analysis of the data examined available cohort sizes, and proportions, means and standard deviations for outcome variables. A series of power calculations was performed for each outcome to estimate the size of the differences between the two OST groups for which the data are powered to detect a difference. ConclusionsData are powered to detect quite small differences, although data available currently do not contain sufficient information to control for confounding and selection biases, necessary to move from descriptions of associations to causal inferences. To address this, client complexity scoring will need to be introduced at entry to treatment.RecommendationsChanges to CRI data collection are recommended to support future work comparing client outcomes." @default.
- W2560983852 created "2017-01-06" @default.
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- W2560983852 date "2015-01-01" @default.
- W2560983852 modified "2023-09-28" @default.
- W2560983852 title "Factors that influence treatment outcome in medically-assisted recovery: an investigation of the feasibility of an observational cohort study based on data from the CRI Information System." @default.
- W2560983852 hasPublicationYear "2015" @default.
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