FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2560996889> ?p ?o ?g. }

• W2560996889 endingPage "6012" @default.
• W2560996889 startingPage "6003" @default.
• W2560996889 abstract "// Feng Xu 1, * , Mengxin Li 1 , Chao Zhang 1 , Jianxiu Cui 1 , Jun Liu 1 , Jie Li 1 , Hongchuan Jiang 1 1 Department of Breast Surgery, Beijing Chao-Yang Hospital, Capital Medical University, Beijing, China, 100020 * Co-first author Correspondence to: Hongchuan Jiang, email: drjhc@sina.com Keywords: breast cancer, COX-2, prognosis, meta-analysis Received: July 04, 2016      Accepted: December 12, 2016      Published: December 16, 2016 ABSTRACT The prognostic significance of COX-2 in patients with breast cancer remains controversial. The aims of our meta-analysis are to evaluate its association with clinicopathological characteristics and prognostic value in patients with breast cancer. PubMed, EMBASE, Web of Science, the Ovid Database and Grey literature were systematically searched up to May 2016. Twenty-one studies including 6739 patients with breast cancer were analyzed. The meta-analysis indicated that the incidence difference of COX-2 expression was significant when comparing the lymph node positive group to negative group (OR = 1.76, 95% CI [1.30, 2.39]) and the tumor size ≥ 2cm group to the tumor size < 2cm group (OR = 1.71, 95% CI [1.22, 2.39]). None of other clinicopathological parameters such as the ER status, PR status, HER2 status and the vascular invasion status were associated with COX-2 overexpression. The detection of COX-2 was significantly correlated with the disease-free survival (DFS) of patients (HR = 1.58, 95% CI [1.23, 2.03]) and the overall survival (OS) of patients (HR = 1.51, 95% CI [1.31, 1.72]). Our meta-analysis demonstrates that the presence of high levels of COX-2 is associated with poor prognosis for breast cancer patients and predicts bigger tumor size and lymph node metastasis." @default.
• W2560996889 created "2017-01-06" @default.
• W2560996889 creator A5005368388 @default.
• W2560996889 creator A5008130258 @default.
• W2560996889 creator A5029568492 @default.
• W2560996889 creator A5046697388 @default.
• W2560996889 creator A5049402835 @default.
• W2560996889 creator A5055588771 @default.
• W2560996889 creator A5068252474 @default.
• W2560996889 date "2016-12-16" @default.
• W2560996889 modified "2023-09-26" @default.
• W2560996889 title "Clinicopathological and prognostic significance of COX-2 immunohistochemical expression in breast cancer: a meta-analysis" @default.
• W2560996889 cites W1531083855 @default.
• W2560996889 cites W1871401516 @default.
• W2560996889 cites W1963705874 @default.
• W2560996889 cites W1964480573 @default.
• W2560996889 cites W1975826537 @default.
• W2560996889 cites W1979423827 @default.
• W2560996889 cites W1982045524 @default.
• W2560996889 cites W1987076210 @default.
• W2560996889 cites W1988619797 @default.
• W2560996889 cites W1997602840 @default.
• W2560996889 cites W2001529630 @default.
• W2560996889 cites W2008308840 @default.
• W2560996889 cites W2014955737 @default.
• W2560996889 cites W2024088948 @default.
• W2560996889 cites W2024425168 @default.
• W2560996889 cites W2038171855 @default.
• W2560996889 cites W2040394747 @default.
• W2560996889 cites W2042033090 @default.
• W2560996889 cites W2043038888 @default.
• W2560996889 cites W2046917725 @default.
• W2560996889 cites W2064897393 @default.
• W2560996889 cites W2068787593 @default.
• W2560996889 cites W2070110479 @default.
• W2560996889 cites W2076862593 @default.
• W2560996889 cites W2088095316 @default.
• W2560996889 cites W2091225458 @default.
• W2560996889 cites W2091892705 @default.
• W2560996889 cites W2096410299 @default.
• W2560996889 cites W2097669235 @default.
• W2560996889 cites W2099052946 @default.
• W2560996889 cites W2100155438 @default.
• W2560996889 cites W2104583717 @default.
• W2560996889 cites W2108577553 @default.
• W2560996889 cites W2110507253 @default.
• W2560996889 cites W2112446944 @default.
• W2560996889 cites W2116475791 @default.
• W2560996889 cites W2121640545 @default.
• W2560996889 cites W2132579331 @default.
• W2560996889 cites W2158960911 @default.
• W2560996889 cites W2169532459 @default.
• W2560996889 cites W2170552969 @default.
• W2560996889 cites W2182509557 @default.
• W2560996889 cites W2200950281 @default.
• W2560996889 cites W2264682931 @default.
• W2560996889 cites W2397006483 @default.
• W2560996889 cites W2588681363 @default.
• W2560996889 cites W42524598 @default.
• W2560996889 doi "https://doi.org/10.18632/oncotarget.13990" @default.
• W2560996889 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/5351608" @default.
• W2560996889 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/27999206" @default.
• W2560996889 hasPublicationYear "2016" @default.
• W2560996889 type Work @default.
• W2560996889 sameAs 2560996889 @default.
• W2560996889 citedByCount "29" @default.
• W2560996889 countsByYear W25609968892017 @default.
• W2560996889 countsByYear W25609968892018 @default.
• W2560996889 countsByYear W25609968892019 @default.
• W2560996889 countsByYear W25609968892020 @default.
• W2560996889 countsByYear W25609968892021 @default.
• W2560996889 countsByYear W25609968892022 @default.
• W2560996889 countsByYear W25609968892023 @default.
• W2560996889 crossrefType "journal-article" @default.
• W2560996889 hasAuthorship W2560996889A5005368388 @default.
• W2560996889 hasAuthorship W2560996889A5008130258 @default.
• W2560996889 hasAuthorship W2560996889A5029568492 @default.
• W2560996889 hasAuthorship W2560996889A5046697388 @default.
• W2560996889 hasAuthorship W2560996889A5049402835 @default.
• W2560996889 hasAuthorship W2560996889A5055588771 @default.
• W2560996889 hasAuthorship W2560996889A5068252474 @default.
• W2560996889 hasBestOaLocation W25609968891 @default.
• W2560996889 hasConcept C120665830 @default.
• W2560996889 hasConcept C121332964 @default.
• W2560996889 hasConcept C121608353 @default.
• W2560996889 hasConcept C126322002 @default.
• W2560996889 hasConcept C143998085 @default.
• W2560996889 hasConcept C50382708 @default.
• W2560996889 hasConcept C530470458 @default.
• W2560996889 hasConcept C61511704 @default.
• W2560996889 hasConcept C71924100 @default.
• W2560996889 hasConcept C95190672 @default.
• W2560996889 hasConceptScore W2560996889C120665830 @default.
• W2560996889 hasConceptScore W2560996889C121332964 @default.
• W2560996889 hasConceptScore W2560996889C121608353 @default.
• W2560996889 hasConceptScore W2560996889C126322002 @default.
• W2560996889 hasConceptScore W2560996889C143998085 @default.
• W2560996889 hasConceptScore W2560996889C50382708 @default.

• next