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• W2561385928 abstract "Six dinuclear platinum(II) complexes with a chiral tetradentate ligand, (1R,1′R,2R,2′R)-N1,N1′-(1,4-phenylenebis(methylene))dicyclohexane-1,2-diamine, have been designed, synthesized and characterized. In vitro cytotoxicity evaluation of these metal complexes against human A549, HCT-116, MCF-7 and HepG-2 cell lines have been carried out. All compounds showed antitumor activity to HepG-2, HCT-116 and A549. Particularly, compounds A1 and A2 exhibited significant better activity than other four compounds and A2 even showed comparable cytotoxicity to cisplatin against HepG-2 cell line." @default.
• W2561385928 created "2017-01-06" @default.
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• W2561385928 date "2017-02-01" @default.
• W2561385928 modified "2023-10-14" @default.
• W2561385928 title "Design, synthesis and biological evaluation of six dinuclear platinum(II) complexes" @default.
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• W2561385928 doi "https://doi.org/10.1016/j.bmcl.2016.12.084" @default.
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