Matches in SemOpenAlex for { <https://semopenalex.org/work/W2561712576> ?p ?o ?g. }
- W2561712576 endingPage "1601967" @default.
- W2561712576 startingPage "1601967" @default.
- W2561712576 abstract "In order to improve the adherence and treatment outcomes of multidrug-resistant (MDR) tuberculosis (TB) patients, the World Health Organization (WHO) has recently recommended a new, shorter and cheaper treatment regimen. The new regimen, comprised of 4–6 months of kanamycin, moxifloxacin, prothionamide, clofazimine, pyrazinamide, ethambutol and high dose isoniazid followed by 5 months of moxifloxacin, clofazimine, pyrazinamide and ethambutol [1], has produced excellent outcomes under operational research conditions is various settings [2–4]. However, the recommendation that it should be used only for MDR-TB patients who are neither previously treated with second-line anti-TB drugs, nor resistant to fluoroquinolones or injectable second-line anti-TB drugs [1], generates concerns about its applicability in MDR-TB high burden countries [5]. In the current cross-sectional study, culture-confirmed MDR-TB patients treated at two units for programmatic management of drug-resistant TB in Pakistan were evaluated for drug resistance pattern and eligibility to be treated with the new shorter regimen. High prevalence of ofloxacin resistance should not limit the applicability of the new shorter regimen in Pakistan <http://ow.ly/HCAs306dUjU> The authors acknowledge the record keeping staff at the study sites for their help in conducting this study, and have no financial support to report and declare no conflict of interest. Author contributions: N. Ahmad, A. Javaid, Z. Shaheen and A.H. Khan designed the study. N. Ahmad, A. Javaid and Z. Shaheen collected the data. N. Ahmad analysed the data and wrote the manuscript. A. Javaid, Z. Shaheen and A.H. Khan critically reviewed the manuscript." @default.
- W2561712576 created "2017-01-06" @default.
- W2561712576 creator A5034666104 @default.
- W2561712576 creator A5039902702 @default.
- W2561712576 creator A5063217856 @default.
- W2561712576 creator A5088273229 @default.
- W2561712576 date "2016-12-19" @default.
- W2561712576 modified "2023-09-24" @default.
- W2561712576 title "Applicability of the World Health Organization recommended new shorter regimen in a multidrug-resistant tuberculosis high burden country" @default.
- W2561712576 cites W1864149440 @default.
- W2561712576 cites W1993951510 @default.
- W2561712576 cites W2007102363 @default.
- W2561712576 cites W2052166920 @default.
- W2561712576 cites W2095281873 @default.
- W2561712576 cites W2156941948 @default.
- W2561712576 cites W2167629505 @default.
- W2561712576 cites W2252023089 @default.
- W2561712576 cites W2417325503 @default.
- W2561712576 cites W2424901174 @default.
- W2561712576 cites W2461516359 @default.
- W2561712576 cites W2512841049 @default.
- W2561712576 cites W2530578798 @default.
- W2561712576 doi "https://doi.org/10.1183/13993003.01967-2016" @default.
- W2561712576 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/28049176" @default.
- W2561712576 hasPublicationYear "2016" @default.
- W2561712576 type Work @default.
- W2561712576 sameAs 2561712576 @default.
- W2561712576 citedByCount "28" @default.
- W2561712576 countsByYear W25617125762017 @default.
- W2561712576 countsByYear W25617125762018 @default.
- W2561712576 countsByYear W25617125762019 @default.
- W2561712576 countsByYear W25617125762020 @default.
- W2561712576 countsByYear W25617125762021 @default.
- W2561712576 countsByYear W25617125762022 @default.
- W2561712576 crossrefType "journal-article" @default.
- W2561712576 hasAuthorship W2561712576A5034666104 @default.
- W2561712576 hasAuthorship W2561712576A5039902702 @default.
- W2561712576 hasAuthorship W2561712576A5063217856 @default.
- W2561712576 hasAuthorship W2561712576A5088273229 @default.
- W2561712576 hasBestOaLocation W25617125761 @default.
- W2561712576 hasConcept C126322002 @default.
- W2561712576 hasConcept C141071460 @default.
- W2561712576 hasConcept C142724271 @default.
- W2561712576 hasConcept C203014093 @default.
- W2561712576 hasConcept C2776228421 @default.
- W2561712576 hasConcept C2776297342 @default.
- W2561712576 hasConcept C2776967927 @default.
- W2561712576 hasConcept C2777975735 @default.
- W2561712576 hasConcept C2778049240 @default.
- W2561712576 hasConcept C2778512257 @default.
- W2561712576 hasConcept C2778836808 @default.
- W2561712576 hasConcept C2780459521 @default.
- W2561712576 hasConcept C2780544761 @default.
- W2561712576 hasConcept C2780695269 @default.
- W2561712576 hasConcept C2781069245 @default.
- W2561712576 hasConcept C2781413609 @default.
- W2561712576 hasConcept C501593827 @default.
- W2561712576 hasConcept C512399662 @default.
- W2561712576 hasConcept C71924100 @default.
- W2561712576 hasConcept C86803240 @default.
- W2561712576 hasConcept C89423630 @default.
- W2561712576 hasConceptScore W2561712576C126322002 @default.
- W2561712576 hasConceptScore W2561712576C141071460 @default.
- W2561712576 hasConceptScore W2561712576C142724271 @default.
- W2561712576 hasConceptScore W2561712576C203014093 @default.
- W2561712576 hasConceptScore W2561712576C2776228421 @default.
- W2561712576 hasConceptScore W2561712576C2776297342 @default.
- W2561712576 hasConceptScore W2561712576C2776967927 @default.
- W2561712576 hasConceptScore W2561712576C2777975735 @default.
- W2561712576 hasConceptScore W2561712576C2778049240 @default.
- W2561712576 hasConceptScore W2561712576C2778512257 @default.
- W2561712576 hasConceptScore W2561712576C2778836808 @default.
- W2561712576 hasConceptScore W2561712576C2780459521 @default.
- W2561712576 hasConceptScore W2561712576C2780544761 @default.
- W2561712576 hasConceptScore W2561712576C2780695269 @default.
- W2561712576 hasConceptScore W2561712576C2781069245 @default.
- W2561712576 hasConceptScore W2561712576C2781413609 @default.
- W2561712576 hasConceptScore W2561712576C501593827 @default.
- W2561712576 hasConceptScore W2561712576C512399662 @default.
- W2561712576 hasConceptScore W2561712576C71924100 @default.
- W2561712576 hasConceptScore W2561712576C86803240 @default.
- W2561712576 hasConceptScore W2561712576C89423630 @default.
- W2561712576 hasIssue "1" @default.
- W2561712576 hasLocation W25617125761 @default.
- W2561712576 hasLocation W25617125762 @default.
- W2561712576 hasOpenAccess W2561712576 @default.
- W2561712576 hasPrimaryLocation W25617125761 @default.
- W2561712576 hasRelatedWork W1954826150 @default.
- W2561712576 hasRelatedWork W2014549521 @default.
- W2561712576 hasRelatedWork W2071711748 @default.
- W2561712576 hasRelatedWork W2125648033 @default.
- W2561712576 hasRelatedWork W2415538921 @default.
- W2561712576 hasRelatedWork W2547197852 @default.
- W2561712576 hasRelatedWork W2561712576 @default.
- W2561712576 hasRelatedWork W2778627706 @default.
- W2561712576 hasRelatedWork W2792244370 @default.
- W2561712576 hasRelatedWork W4385956814 @default.
- W2561712576 hasVolume "49" @default.