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- W2561998310 abstract "Objectives This study is evaluating fetuin-A, serum amyloid A (SAA) and tumor necrosis factor alpha (TNF-α) levels in gingival crevicular fluid (GCF) and serum samples in periodontal health and disease. Material and Methods Sixty patients were divided into three groups: Group 1 periodontal health (n = 20), Group 2 gingivitis (n = 20) and Group 3 chronic periodontitis (CP) (n = 20). GCF and serum samples were evaluated using enzyme-linked immunosorbent assay kit. Results SAA and TNF-α levels in GCF and serum were significantly higher in patients with gingivitis and CP compared with controls (P < 0.016). Contrarily, fetuin-A levels in GCF and serum were significantly higher in controls than in patients with gingivitis and CP (P < 0.016). In CP group, a significant correlation was observed between GCF-SAA amount and the number of sites with 4 ≤ PPD ≤ 5 mm (P < 0.05). There was a significant correlation between GCF-fetuin-A levels and the number of sites with PPD ≥ 6 mm (P < 0.05). GCF-TNF-α was found to have a significant relationship with the number of sites with 4 ≤ PPD ≤ 5 mm and PPD ≥ 6 mm (P < 0.05). Conclusions In conclusion, serum and total levels of SAA significantly increased, whereas fetuin-A levels significantly decreased, with increasing severity of PD." @default.
- W2561998310 created "2017-01-06" @default.
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- W2561998310 date "2017-01-24" @default.
- W2561998310 modified "2023-10-14" @default.
- W2561998310 title "Fetuin-A, serum amyloid A and tumor necrosis factor alpha levels in periodontal health and disease" @default.
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- W2561998310 doi "https://doi.org/10.1111/odi.12625" @default.
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