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- W2562111566 abstract "Leukotriene B4 receptor 1 (BLT1), a high-affinity G protein-coupled receptor (GPCR) for leukotriene B4 (LTB4), plays important roles in inflammatory and immune reactions. Although the LTB4-BLT1 axis is known to promote inflammation, the binding proteins that modulate LTB4-BLT1 signaling have not been identified. Recently, we discovered that receptor for advanced glycation end products (RAGE) interacts with BLT1 and modulates LTB4-BLT1 signaling. We propose RAGE as a new class of GPCR modulator and a new target of future GPCR studies." @default.
- W2562111566 created "2017-01-06" @default.
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- W2562111566 date "2016-12-01" @default.
- W2562111566 modified "2023-09-25" @default.
- W2562111566 title "Receptor for Advanced Glycation End Products Regulates Leukotriene B<sub>4</sub>Receptor 1 Signaling" @default.
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- W2562111566 doi "https://doi.org/10.1089/dna.2016.3552" @default.
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