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• W2562187624 abstract "This study investigated a new and easy-to-industrialized extracting method for curcumin from Curcuma longa rhizomes using ultrasonic extraction technology combined with ammonium sulfate/ethanol aqueous two-phase system (ATPS), and the preparation of curcumin using the semi-preparative HPLC. The single-factor experiments and response surface methodology (RSM) were utilized to determine the optimal material-solvent ratio, ultrasonic intensity (UI) and ultrasonic time. The optimum extraction conditions were finally determined to be material-solvent rate of 3.29:100, ultrasonic intensity of 33.63 W/cm2 and ultrasonic time of 17 min. At these optimum conditions, the extraction yield could reach 46.91 mg/g. And the extraction yields of curcumin remained stable in the case of amplification, which indicated that scale-up extraction was feasible and efficient. Afterwards, the semi-preparative HPLC experiment was carried out, in which optimal preparation conditions were elected according to the single factor experiment. The prepared curcumin was obtained and the purity could up to 85.58% by the semi-preparative HPLC." @default.
• W2562187624 created "2017-01-06" @default.
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• W2562187624 date "2017-01-01" @default.
• W2562187624 modified "2023-10-16" @default.
• W2562187624 title "A method for the preparation of curcumin by ultrasonic-assisted ammonium sulfate/ethanol aqueous two phase extraction" @default.
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• W2562187624 doi "https://doi.org/10.1016/j.jchromb.2016.12.029" @default.
• W2562187624 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/28043027" @default.
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