FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2562523962> ?p ?o ?g. }

• W2562523962 endingPage "3932" @default.
• W2562523962 startingPage "3895" @default.
• W2562523962 abstract "// Alexander V. Ivanov 1 , Vladimir T. Valuev-Elliston 1 , Daria A. Tyurina 1 , Olga N. Ivanova 1 , Sergey N. Kochetkov 1 , Birke Bartosch 2,3 and Maria G. Isaguliants 4,5 1 Engelhardt Institute of Molecular Biology, Russian Academy of Sciences, Moscow, Russia 2 Inserm U1052, Cancer Research Center Lyon, University of Lyon, Lyon, France 3 DevWeCan Laboratories of Excellence Network, France 4 Riga Stradins University, Riga, Latvia 5 Department of Microbiology, Tumor and Cell Biology, Karolinska Institutet, Stockholm, Sweden Correspondence to: Alexander V. Ivanov, email: // Maria G. Isaguliants, email: // Keywords : hepatitis C virus, hepatitis B virus, reactive oxygen species, pathogenesis, carcinogenesis Received : July 22, 2016 Accepted : December 05, 2016 Published : December 11, 2016 Abstract Virally induced liver cancer usually evolves over long periods of time in the context of a strongly oxidative microenvironment, characterized by chronic liver inflammation and regeneration processes. They ultimately lead to oncogenic mutations in many cellular signaling cascades that drive cell growth and proliferation. Oxidative stress, induced by hepatitis viruses, therefore is one of the factors that drives the neoplastic transformation process in the liver. This review summarizes current knowledge on oxidative stress and oxidative stress responses induced by human hepatitis B and C viruses. It focuses on the molecular mechanisms by which these viruses activate cellular enzymes/systems that generate or scavenge reactive oxygen species (ROS) and control cellular redox homeostasis. The impact of an altered cellular redox homeostasis on the initiation and establishment of chronic viral infection, as well as on the course and outcome of liver fibrosis and hepatocarcinogenesis will be discussed The review neither discusses reactive nitrogen species, although their metabolism is interferes with that of ROS, nor antioxidants as potential therapeutic remedies against viral infections, both subjects meriting an independent review." @default.
• W2562523962 created "2017-01-06" @default.
• W2562523962 creator A5014770973 @default.
• W2562523962 creator A5014873443 @default.
• W2562523962 creator A5015552741 @default.
• W2562523962 creator A5040763459 @default.
• W2562523962 creator A5044978887 @default.
• W2562523962 creator A5058174908 @default.
• W2562523962 creator A5081056114 @default.
• W2562523962 date "2016-12-11" @default.
• W2562523962 modified "2023-10-11" @default.
• W2562523962 title "Oxidative stress, a trigger of hepatitis C and B virus-induced liver carcinogenesis" @default.
• W2562523962 cites W1447364984 @default.
• W2562523962 cites W1487503477 @default.
• W2562523962 cites W1489883635 @default.
• W2562523962 cites W1518228374 @default.
• W2562523962 cites W1521019257 @default.
• W2562523962 cites W1531285870 @default.
• W2562523962 cites W1534562881 @default.
• W2562523962 cites W1534927179 @default.
• W2562523962 cites W1535124446 @default.
• W2562523962 cites W1537971445 @default.
• W2562523962 cites W1541248464 @default.
• W2562523962 cites W1541295298 @default.
• W2562523962 cites W1553367038 @default.
• W2562523962 cites W1591803455 @default.
• W2562523962 cites W174228821 @default.
• W2562523962 cites W1743171475 @default.
• W2562523962 cites W1751298600 @default.
• W2562523962 cites W1757407923 @default.
• W2562523962 cites W1759342672 @default.
• W2562523962 cites W1795451786 @default.
• W2562523962 cites W1824414858 @default.
• W2562523962 cites W1835730169 @default.
• W2562523962 cites W1838530486 @default.
• W2562523962 cites W1855224084 @default.
• W2562523962 cites W1865640430 @default.
• W2562523962 cites W1927008944 @default.
• W2562523962 cites W1945992367 @default.
• W2562523962 cites W1964054989 @default.
• W2562523962 cites W1964185091 @default.
• W2562523962 cites W1965213577 @default.
• W2562523962 cites W1965501203 @default.
• W2562523962 cites W1968552098 @default.
• W2562523962 cites W1968569852 @default.
• W2562523962 cites W1970050679 @default.
• W2562523962 cites W1970237293 @default.
• W2562523962 cites W1970430388 @default.
• W2562523962 cites W1971689602 @default.
• W2562523962 cites W1971884054 @default.
• W2562523962 cites W1972176308 @default.
• W2562523962 cites W1972290395 @default.
• W2562523962 cites W1973673595 @default.
• W2562523962 cites W1973849569 @default.
• W2562523962 cites W1974628692 @default.
• W2562523962 cites W1975280933 @default.
• W2562523962 cites W1975538583 @default.
• W2562523962 cites W1976619282 @default.
• W2562523962 cites W1976887467 @default.
• W2562523962 cites W1977279106 @default.
• W2562523962 cites W1978474161 @default.
• W2562523962 cites W1979159846 @default.
• W2562523962 cites W1979170294 @default.
• W2562523962 cites W1980024259 @default.
• W2562523962 cites W1981278169 @default.
• W2562523962 cites W1981634750 @default.
• W2562523962 cites W1982515947 @default.
• W2562523962 cites W1983154697 @default.
• W2562523962 cites W1984534635 @default.
• W2562523962 cites W1984590625 @default.
• W2562523962 cites W1984672460 @default.
• W2562523962 cites W1985493306 @default.
• W2562523962 cites W1985778063 @default.
• W2562523962 cites W1986370482 @default.
• W2562523962 cites W1986506089 @default.
• W2562523962 cites W1988544363 @default.
• W2562523962 cites W1988570369 @default.
• W2562523962 cites W1989368291 @default.
• W2562523962 cites W1990057839 @default.
• W2562523962 cites W1990184306 @default.
• W2562523962 cites W1990817456 @default.
• W2562523962 cites W1990932508 @default.
• W2562523962 cites W1991952977 @default.
• W2562523962 cites W1992385844 @default.
• W2562523962 cites W1993340120 @default.
• W2562523962 cites W1994056355 @default.
• W2562523962 cites W1994742809 @default.
• W2562523962 cites W1996024251 @default.
• W2562523962 cites W1996196897 @default.
• W2562523962 cites W1996327054 @default.
• W2562523962 cites W1996986771 @default.
• W2562523962 cites W1997530090 @default.
• W2562523962 cites W1998284663 @default.
• W2562523962 cites W1999030622 @default.
• W2562523962 cites W1999157020 @default.
• W2562523962 cites W2000069042 @default.
• W2562523962 cites W2000379709 @default.
• W2562523962 cites W2000581759 @default.

• next