Matches in SemOpenAlex for { <https://semopenalex.org/work/W2562606989> ?p ?o ?g. }
Showing items 1 to 81 of
81
with 100 items per page.
- W2562606989 endingPage "50" @default.
- W2562606989 startingPage "44" @default.
- W2562606989 abstract "It has been reported that as compared with total intravenous anesthesia (TIVA), inhalation anesthesia is increasing the postoperative level of proinflammatory interleukins.The aim of the study is to investigate if there is an in-vivo relationship between proinflammatory cytokines, Interleukin-32 (IL-32) and Tumour necrosis factor - α (TNF-α), in patients undergoing laparoscopic cholecystectomies with two different anesthetic techniques, TIVA or inhalation anesthesia.Twenty two consecutive patients undergoing laparoscopic cholecystectomies were prospectively randomized into two groups: Group 1: TIVA with target-controlled infusion (TIVA-TCI) (n=11) and Group 2: isoflurane anesthesia (ISO) (n=11). IL-32 and TNF-α were determined before the induction of anesthesia (T1), before incision (T2) and at 2h (T3) and 24h (T4) postoperatively. Our primary outcome was to compare plasma levels of IL-32 and TNF-α concentrations (expressed as area-under-the-curve) over 24 hours between study groups. Our secondary outcome was to establish whether there is a correlation between plasma levels of IL-32 and of TNF-α at each time point between the two groups.Area-under-the-curve (AUC) of IL-32 plasma concentration was 7.53 in Group 1 (TIVA) versus 3.80 in Group 2 (ISO), p= 1. For TNF-α, AUC of plasma concentration was 733.9 in Group 1 (TIVA) and 668.7 in Group 2 (ISO), p=0.066. There were no significant differences in plasma concentrations of both IL-32 and TNF-α between the groups.IL-32 expression in response to minor surgery is very low. There were no significant difference between plasma levels of TNF-α and IL-32 after TIVA versus inhalation anesthesia during the first 24 hours postoperatively. Further studies are needed on larger groups to investigate whether there can be a correlation between these interleukins after 2 different anesthetic techniques and the impact of this correlation on postoperative outcome." @default.
- W2562606989 created "2017-01-06" @default.
- W2562606989 creator A5023405873 @default.
- W2562606989 creator A5050223949 @default.
- W2562606989 creator A5052555098 @default.
- W2562606989 creator A5063346963 @default.
- W2562606989 creator A5084613314 @default.
- W2562606989 date "2016-01-01" @default.
- W2562606989 modified "2023-09-24" @default.
- W2562606989 title "Total Intravenous Versus Inhalation Anesthesia in Patients Undergoing Laparoscopic Cholecystectomies. Effects on Two Proinflammatory Cytokines Serum Levels: Il-32 and TNF-Alfa." @default.
- W2562606989 cites W1970717332 @default.
- W2562606989 cites W1971104501 @default.
- W2562606989 cites W1997402936 @default.
- W2562606989 cites W2042804855 @default.
- W2562606989 cites W2057828074 @default.
- W2562606989 cites W2083841175 @default.
- W2562606989 cites W2089358636 @default.
- W2562606989 cites W2105483512 @default.
- W2562606989 cites W2150081271 @default.
- W2562606989 cites W2159732031 @default.
- W2562606989 cites W2164592060 @default.
- W2562606989 cites W70197470 @default.
- W2562606989 doi "https://doi.org/10.1515/jccm-2016-0008" @default.
- W2562606989 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/5939142" @default.
- W2562606989 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/29967836" @default.
- W2562606989 hasPublicationYear "2016" @default.
- W2562606989 type Work @default.
- W2562606989 sameAs 2562606989 @default.
- W2562606989 citedByCount "2" @default.
- W2562606989 countsByYear W25626069892019 @default.
- W2562606989 crossrefType "journal-article" @default.
- W2562606989 hasAuthorship W2562606989A5023405873 @default.
- W2562606989 hasAuthorship W2562606989A5050223949 @default.
- W2562606989 hasAuthorship W2562606989A5052555098 @default.
- W2562606989 hasAuthorship W2562606989A5063346963 @default.
- W2562606989 hasAuthorship W2562606989A5084613314 @default.
- W2562606989 hasBestOaLocation W25626069891 @default.
- W2562606989 hasConcept C126322002 @default.
- W2562606989 hasConcept C164027704 @default.
- W2562606989 hasConcept C17991360 @default.
- W2562606989 hasConcept C2776359302 @default.
- W2562606989 hasConcept C2776914184 @default.
- W2562606989 hasConcept C2776954882 @default.
- W2562606989 hasConcept C2778162923 @default.
- W2562606989 hasConcept C42219234 @default.
- W2562606989 hasConcept C71924100 @default.
- W2562606989 hasConcept C90924648 @default.
- W2562606989 hasConceptScore W2562606989C126322002 @default.
- W2562606989 hasConceptScore W2562606989C164027704 @default.
- W2562606989 hasConceptScore W2562606989C17991360 @default.
- W2562606989 hasConceptScore W2562606989C2776359302 @default.
- W2562606989 hasConceptScore W2562606989C2776914184 @default.
- W2562606989 hasConceptScore W2562606989C2776954882 @default.
- W2562606989 hasConceptScore W2562606989C2778162923 @default.
- W2562606989 hasConceptScore W2562606989C42219234 @default.
- W2562606989 hasConceptScore W2562606989C71924100 @default.
- W2562606989 hasConceptScore W2562606989C90924648 @default.
- W2562606989 hasIssue "1" @default.
- W2562606989 hasLocation W25626069891 @default.
- W2562606989 hasLocation W25626069892 @default.
- W2562606989 hasLocation W25626069893 @default.
- W2562606989 hasLocation W25626069894 @default.
- W2562606989 hasOpenAccess W2562606989 @default.
- W2562606989 hasPrimaryLocation W25626069891 @default.
- W2562606989 hasRelatedWork W1949399753 @default.
- W2562606989 hasRelatedWork W2012680029 @default.
- W2562606989 hasRelatedWork W2013222278 @default.
- W2562606989 hasRelatedWork W2034833030 @default.
- W2562606989 hasRelatedWork W2081597172 @default.
- W2562606989 hasRelatedWork W2109339841 @default.
- W2562606989 hasRelatedWork W2357885979 @default.
- W2562606989 hasRelatedWork W2361962396 @default.
- W2562606989 hasRelatedWork W2389895138 @default.
- W2562606989 hasRelatedWork W3028914160 @default.
- W2562606989 hasVolume "2" @default.
- W2562606989 isParatext "false" @default.
- W2562606989 isRetracted "false" @default.
- W2562606989 magId "2562606989" @default.
- W2562606989 workType "article" @default.