Matches in SemOpenAlex for { <https://semopenalex.org/work/W2563211126> ?p ?o ?g. }
- W2563211126 endingPage "397" @default.
- W2563211126 startingPage "387" @default.
- W2563211126 abstract "Etiopathogenesis of VUR is composite and not fully understood. Many data indicate the importance of genetic predisposition. The aim of this study was to establish the relationship of selected polymorphisms: 14094 polymorphism of the ACE, polymorphism rs1800469 of TGFβ-1, rs5443 gene polymorphism of the GNB3 and receptor gene polymorphism rs5186 type 1 AGTR1 with the occurrence of the primary vesicoureteral reflux. The study included 190 children: 90 with the primary VUR confirmed with the voiding cystourethrogram and excluded secondary VUR and a control group of 100 children without a history of the diseases of the genitourinary tract. The study was planned in the scheme: “tested case versus control.” Genomic DNA was isolated from the leukocytes of peripheral blood samples. The results were statistically analyzed in the Statistica 10 using χ 2 test and analysis of the variance Anova. Any of the four studied polymorphisms showed no difference in the distribution of genotypes between patients with primary vesicoureteral reflux and the control group. In patients with VUR and TT genotype polymorphism rs5443 GNB3 gene, the glomerular filtration rate was significantly higher than in patients with genotype CC or CT. (1) No relationship was found between the studied polymorphisms (14094 ACE gene, rs1800469 gene TGFβ1, GNB3 gene rs5443, rs5186 AGTR1 gene) and the occurrence of primary vesicoureteral reflux. (2) TT genotype polymorphism rs5443 GNB3 gene may be a protective factor for the improved renal function in patients with primary vesicoureteral reflux in patients with genotype CC or CT." @default.
- W2563211126 created "2017-01-06" @default.
- W2563211126 creator A5022875857 @default.
- W2563211126 creator A5041237767 @default.
- W2563211126 creator A5046723130 @default.
- W2563211126 creator A5057777286 @default.
- W2563211126 creator A5076306340 @default.
- W2563211126 creator A5043268440 @default.
- W2563211126 date "2016-12-17" @default.
- W2563211126 modified "2023-09-30" @default.
- W2563211126 title "Estimation of the relationship between the polymorphisms of selected genes: ACE, AGTR1, TGFβ1 and GNB3 with the occurrence of primary vesicoureteral reflux" @default.
- W2563211126 cites W1529081960 @default.
- W2563211126 cites W1556358266 @default.
- W2563211126 cites W1560512674 @default.
- W2563211126 cites W1562821905 @default.
- W2563211126 cites W1585063521 @default.
- W2563211126 cites W1652794559 @default.
- W2563211126 cites W1936789480 @default.
- W2563211126 cites W1969716641 @default.
- W2563211126 cites W1973698874 @default.
- W2563211126 cites W1977411948 @default.
- W2563211126 cites W1979443446 @default.
- W2563211126 cites W1984212762 @default.
- W2563211126 cites W1984242083 @default.
- W2563211126 cites W1984938230 @default.
- W2563211126 cites W1986662064 @default.
- W2563211126 cites W1986847249 @default.
- W2563211126 cites W1992705057 @default.
- W2563211126 cites W1996837509 @default.
- W2563211126 cites W1999295622 @default.
- W2563211126 cites W2001437386 @default.
- W2563211126 cites W2004731491 @default.
- W2563211126 cites W2005365259 @default.
- W2563211126 cites W2005443309 @default.
- W2563211126 cites W2005760713 @default.
- W2563211126 cites W2011896213 @default.
- W2563211126 cites W2013709047 @default.
- W2563211126 cites W2017545530 @default.
- W2563211126 cites W2018736970 @default.
- W2563211126 cites W2019733034 @default.
- W2563211126 cites W2020123276 @default.
- W2563211126 cites W2020202045 @default.
- W2563211126 cites W2022709532 @default.
- W2563211126 cites W2023725307 @default.
- W2563211126 cites W2025629823 @default.
- W2563211126 cites W2027331172 @default.
- W2563211126 cites W2033708883 @default.
- W2563211126 cites W2033984643 @default.
- W2563211126 cites W2034473329 @default.
- W2563211126 cites W2034801563 @default.
- W2563211126 cites W2035046423 @default.
- W2563211126 cites W2036912869 @default.
- W2563211126 cites W2043523429 @default.
- W2563211126 cites W2044980688 @default.
- W2563211126 cites W2049489756 @default.
- W2563211126 cites W2050496738 @default.
- W2563211126 cites W2057840935 @default.
- W2563211126 cites W2058929428 @default.
- W2563211126 cites W2062326841 @default.
- W2563211126 cites W2064054368 @default.
- W2563211126 cites W2064803261 @default.
- W2563211126 cites W2066109743 @default.
- W2563211126 cites W2068406686 @default.
- W2563211126 cites W2069197415 @default.
- W2563211126 cites W2069313150 @default.
- W2563211126 cites W2069631287 @default.
- W2563211126 cites W2070015555 @default.
- W2563211126 cites W2070250721 @default.
- W2563211126 cites W2071105324 @default.
- W2563211126 cites W2074854626 @default.
- W2563211126 cites W2074936751 @default.
- W2563211126 cites W2078371200 @default.
- W2563211126 cites W2083818429 @default.
- W2563211126 cites W2085241762 @default.
- W2563211126 cites W2093281175 @default.
- W2563211126 cites W2093433538 @default.
- W2563211126 cites W2094591155 @default.
- W2563211126 cites W2097485721 @default.
- W2563211126 cites W2100851968 @default.
- W2563211126 cites W2102355085 @default.
- W2563211126 cites W2103891659 @default.
- W2563211126 cites W2104586199 @default.
- W2563211126 cites W2106816660 @default.
- W2563211126 cites W2109183823 @default.
- W2563211126 cites W2109384327 @default.
- W2563211126 cites W2111304563 @default.
- W2563211126 cites W2111560295 @default.
- W2563211126 cites W2111660129 @default.
- W2563211126 cites W2113350447 @default.
- W2563211126 cites W2115536580 @default.
- W2563211126 cites W2125142132 @default.
- W2563211126 cites W2125749178 @default.
- W2563211126 cites W2126498031 @default.
- W2563211126 cites W2129268944 @default.
- W2563211126 cites W2130046770 @default.
- W2563211126 cites W2134955857 @default.
- W2563211126 cites W2135029031 @default.
- W2563211126 cites W2135587043 @default.