Matches in SemOpenAlex for { <https://semopenalex.org/work/W2563244803> ?p ?o ?g. }
- W2563244803 endingPage "261" @default.
- W2563244803 startingPage "245" @default.
- W2563244803 abstract "The recently identified mechanically activated Piezo1 and Piezo2 channels play major roles in various aspects of mechanosensation in mammals, and their mutations are associated with human diseases. Recent reports show that activation of cell surface receptors coupled to heterotrimeric Gq proteins increase the sensitivity of Piezo2 channels to mechanical stimuli. Activation of the cyclic adenosine monophosphate pathway was also shown to potentiate Piezo2 channel activity. This phenomenon may play a role in mechanical allodynia or hyperalgesia during inflammation. Both Piezo1 and Piezo2 channels are inhibited upon depletion of plasma membrane phosphoinositides, in response to phospholipase C activation by Ca2+ influx via the transient receptor potential vanilloid 1 channels. This review will discuss current knowledge on regulation of Piezo channels by these intracellular signaling pathways." @default.
- W2563244803 created "2017-01-06" @default.
- W2563244803 creator A5003816641 @default.
- W2563244803 creator A5068881900 @default.
- W2563244803 date "2017-01-01" @default.
- W2563244803 modified "2023-10-14" @default.
- W2563244803 title "Regulation of Piezo Channels by Cellular Signaling Pathways" @default.
- W2563244803 cites W1562125341 @default.
- W2563244803 cites W183810266 @default.
- W2563244803 cites W1883732752 @default.
- W2563244803 cites W1884196201 @default.
- W2563244803 cites W1969891332 @default.
- W2563244803 cites W1976176467 @default.
- W2563244803 cites W1983897833 @default.
- W2563244803 cites W1985030046 @default.
- W2563244803 cites W1986235007 @default.
- W2563244803 cites W1991643569 @default.
- W2563244803 cites W1994285472 @default.
- W2563244803 cites W1995705528 @default.
- W2563244803 cites W1999720993 @default.
- W2563244803 cites W2000617404 @default.
- W2563244803 cites W2007949464 @default.
- W2563244803 cites W2012009579 @default.
- W2563244803 cites W2016194590 @default.
- W2563244803 cites W2030665240 @default.
- W2563244803 cites W2030986287 @default.
- W2563244803 cites W2034576125 @default.
- W2563244803 cites W2035330601 @default.
- W2563244803 cites W2041363373 @default.
- W2563244803 cites W2044832274 @default.
- W2563244803 cites W2047012091 @default.
- W2563244803 cites W2048894410 @default.
- W2563244803 cites W2050781058 @default.
- W2563244803 cites W2054088330 @default.
- W2563244803 cites W2064374911 @default.
- W2563244803 cites W2065676350 @default.
- W2563244803 cites W2079597091 @default.
- W2563244803 cites W2083824794 @default.
- W2563244803 cites W2085035388 @default.
- W2563244803 cites W2092526634 @default.
- W2563244803 cites W2104154771 @default.
- W2563244803 cites W2106699401 @default.
- W2563244803 cites W2107634021 @default.
- W2563244803 cites W2111904037 @default.
- W2563244803 cites W2113755495 @default.
- W2563244803 cites W2115565372 @default.
- W2563244803 cites W2126312769 @default.
- W2563244803 cites W2130600650 @default.
- W2563244803 cites W2134555179 @default.
- W2563244803 cites W2134577432 @default.
- W2563244803 cites W2134742719 @default.
- W2563244803 cites W2143897453 @default.
- W2563244803 cites W2145433577 @default.
- W2563244803 cites W2149079172 @default.
- W2563244803 cites W2155469071 @default.
- W2563244803 cites W2161535250 @default.
- W2563244803 cites W2162228329 @default.
- W2563244803 cites W2165048396 @default.
- W2563244803 cites W2184968222 @default.
- W2563244803 cites W2223734153 @default.
- W2563244803 cites W2256087259 @default.
- W2563244803 cites W2260991120 @default.
- W2563244803 cites W2290636465 @default.
- W2563244803 cites W4243559800 @default.
- W2563244803 cites W4253230296 @default.
- W2563244803 doi "https://doi.org/10.1016/bs.ctm.2016.10.002" @default.
- W2563244803 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6464384" @default.
- W2563244803 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/28728819" @default.
- W2563244803 hasPublicationYear "2017" @default.
- W2563244803 type Work @default.
- W2563244803 sameAs 2563244803 @default.
- W2563244803 citedByCount "21" @default.
- W2563244803 countsByYear W25632448032018 @default.
- W2563244803 countsByYear W25632448032019 @default.
- W2563244803 countsByYear W25632448032020 @default.
- W2563244803 countsByYear W25632448032021 @default.
- W2563244803 countsByYear W25632448032022 @default.
- W2563244803 countsByYear W25632448032023 @default.
- W2563244803 crossrefType "book-chapter" @default.
- W2563244803 hasAuthorship W2563244803A5003816641 @default.
- W2563244803 hasAuthorship W2563244803A5068881900 @default.
- W2563244803 hasBestOaLocation W25632448032 @default.
- W2563244803 hasConcept C135285700 @default.
- W2563244803 hasConcept C139407321 @default.
- W2563244803 hasConcept C155164980 @default.
- W2563244803 hasConcept C158617107 @default.
- W2563244803 hasConcept C162740809 @default.
- W2563244803 hasConcept C169760540 @default.
- W2563244803 hasConcept C170488646 @default.
- W2563244803 hasConcept C170493617 @default.
- W2563244803 hasConcept C181104049 @default.
- W2563244803 hasConcept C185592680 @default.
- W2563244803 hasConcept C25194021 @default.
- W2563244803 hasConcept C2776610495 @default.
- W2563244803 hasConcept C2776668983 @default.
- W2563244803 hasConcept C2778597717 @default.
- W2563244803 hasConcept C2780785647 @default.
- W2563244803 hasConcept C4001165 @default.