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• W2563294686 abstract "Extracellular signals are received by receptors present at the cell surface, and the information encoded in these signals is transmitted inside the cell, its biochemical machinery eliciting biological responses. The sequencing of the Plasmodium genome and subsequent bioinformatics and computational analyses indicated the presence of several interesting gene and protein families in the parasite. This chapter discusses some of the features of Plasmodium signaling regulated by second messengers like calcium, phosphoinositides, and cyclic nucleotides. The malaria parasite contains several eukaryotic protein kinases, which includes eukaryotic-like protein kinases (ePK) and atypical protein kinases (aPK). Several signaling proteins are essential for the development of asexual blood stage parasite. A multidisciplinary approach, which combines the traditional and the modern high-throughput approaches like genomics, proteomics, and chemical and systems biology will hopefully lead to the development of parasite-signaling maps, as is the case with other organisms." @default.
• W2563294686 created "2017-01-06" @default.
• W2563294686 creator A5009984025 @default.
• W2563294686 creator A5041282587 @default.
• W2563294686 date "2016-12-08" @default.
• W2563294686 modified "2023-10-16" @default.
• W2563294686 title "Signaling in malaria parasites" @default.
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