Matches in SemOpenAlex for { <https://semopenalex.org/work/W2563465120> ?p ?o ?g. }
Showing items 1 to 68 of
68
with 100 items per page.
- W2563465120 abstract "Background: Seroprevalence of human herpesvirus type 8 (HHV-8) is high in patients with various immunologic abnormalities. Patients with chronic pulmonary disease (COPD) are immunocompromised, but the prevalence of HHV-8 in COPD patientsremains unclear. Aims and objectives: To compare HHV-8 seroprevalence in COPD patients and healthy controls. Methods: Blood samples collected from 64 COPD patients and 64 age- and sex-matched healthy controls were used to determine hemogram, HHV-8 antibody level, and HHV-8 DNA level. Results: COPD patients had a significantly lower lymphocyte count and a higher monocyte count than the healthy controls ( P = 0.0006 and 0.0003, respectively). The seroprevalence of HHV-8 antibodies was moderately higher in COPD patients than in controls (37.5% vs. 26.6%, P = 0.18). Three patients positive for HHV-8 antibodies (1:40, 1:160, and 1:640) were also positive for HHV-8 DNA (2,090, 133, and 1,450 copies/mL, respectively). Lymphocyte counts were significantly higher in COPD patients positive for HHV-8 antibodies than in negatives (1,609±925/mL vs. 1,106±548/mL, P = 0.014; t test) and in COPD patients positive for HHV-8 DNA than in negatives (2,576±786/mL vs. 1,448±861/mL, P = 0.048; t test). Furthermore, lymphocyte count increased (from 1,688 to 2,856 and 3,184 cells/mL) with increasing HHV-8 viral load (from 133 to 1,450 and 2,090 copies/mL). Conclusions: HHV-8 seroprevalence is moderately higher in COPD patients than in healthy controls, and lymphocyte count is significantly higher in COPD patients positive for HHV-8 antibodies or HHV-8 DNA than in negatives. Lymphocyte count increases with increase in HHV-8 viral load in patients positive for HHV-8 DNA." @default.
- W2563465120 created "2017-01-06" @default.
- W2563465120 creator A5032449545 @default.
- W2563465120 creator A5059211567 @default.
- W2563465120 creator A5063808289 @default.
- W2563465120 creator A5075454902 @default.
- W2563465120 creator A5085364091 @default.
- W2563465120 date "2015-09-01" @default.
- W2563465120 modified "2023-10-17" @default.
- W2563465120 title "Human herpesvirus type 8 in patients with chronic obstructive pulmonary disease" @default.
- W2563465120 doi "https://doi.org/10.1183/13993003.congress-2015.pa3655" @default.
- W2563465120 hasPublicationYear "2015" @default.
- W2563465120 type Work @default.
- W2563465120 sameAs 2563465120 @default.
- W2563465120 citedByCount "0" @default.
- W2563465120 crossrefType "proceedings-article" @default.
- W2563465120 hasAuthorship W2563465120A5032449545 @default.
- W2563465120 hasAuthorship W2563465120A5059211567 @default.
- W2563465120 hasAuthorship W2563465120A5063808289 @default.
- W2563465120 hasAuthorship W2563465120A5075454902 @default.
- W2563465120 hasAuthorship W2563465120A5085364091 @default.
- W2563465120 hasConcept C126322002 @default.
- W2563465120 hasConcept C159654299 @default.
- W2563465120 hasConcept C203014093 @default.
- W2563465120 hasConcept C2776780178 @default.
- W2563465120 hasConcept C2777761686 @default.
- W2563465120 hasConcept C2778494684 @default.
- W2563465120 hasConcept C2992779976 @default.
- W2563465120 hasConcept C45189115 @default.
- W2563465120 hasConcept C71924100 @default.
- W2563465120 hasConcept C90924648 @default.
- W2563465120 hasConceptScore W2563465120C126322002 @default.
- W2563465120 hasConceptScore W2563465120C159654299 @default.
- W2563465120 hasConceptScore W2563465120C203014093 @default.
- W2563465120 hasConceptScore W2563465120C2776780178 @default.
- W2563465120 hasConceptScore W2563465120C2777761686 @default.
- W2563465120 hasConceptScore W2563465120C2778494684 @default.
- W2563465120 hasConceptScore W2563465120C2992779976 @default.
- W2563465120 hasConceptScore W2563465120C45189115 @default.
- W2563465120 hasConceptScore W2563465120C71924100 @default.
- W2563465120 hasConceptScore W2563465120C90924648 @default.
- W2563465120 hasLocation W25634651201 @default.
- W2563465120 hasOpenAccess W2563465120 @default.
- W2563465120 hasPrimaryLocation W25634651201 @default.
- W2563465120 hasRelatedWork W142923072 @default.
- W2563465120 hasRelatedWork W1918941859 @default.
- W2563465120 hasRelatedWork W2010923045 @default.
- W2563465120 hasRelatedWork W2152828604 @default.
- W2563465120 hasRelatedWork W2185195218 @default.
- W2563465120 hasRelatedWork W2191069972 @default.
- W2563465120 hasRelatedWork W2327165195 @default.
- W2563465120 hasRelatedWork W2372140970 @default.
- W2563465120 hasRelatedWork W2372892883 @default.
- W2563465120 hasRelatedWork W2391586814 @default.
- W2563465120 hasRelatedWork W2465306783 @default.
- W2563465120 hasRelatedWork W2527050971 @default.
- W2563465120 hasRelatedWork W2808398116 @default.
- W2563465120 hasRelatedWork W3015072713 @default.
- W2563465120 hasRelatedWork W3025914515 @default.
- W2563465120 hasRelatedWork W3030501850 @default.
- W2563465120 hasRelatedWork W3083832945 @default.
- W2563465120 hasRelatedWork W3205959756 @default.
- W2563465120 hasRelatedWork W3207495733 @default.
- W2563465120 hasRelatedWork W2566375864 @default.
- W2563465120 isParatext "false" @default.
- W2563465120 isRetracted "false" @default.
- W2563465120 magId "2563465120" @default.
- W2563465120 workType "article" @default.