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• W2563490400 abstract "e11121 Background: To better understand burden of illness in women with HER2+ metastatic breast cancer (MBC), we conducted a survey to evaluate their treatment experiences. Methods: This one-time, web-based survey was conducted with the help of 4 independent U.S. breast cancer support groups. Respondents were invited to participate via email, and were required to be female, aged 18+ with HER2+ MBC, and to have received active treatment in the past month. Approximately 100 demographic, clinical, employment, quality of life, social and resource use data items were collected. Results: 130 women with HER2+ MBC completed the survey. The majority of respondents were 45-59 years old (54.6%), white (93.9%), living with a spouse or partner (72.3%) and had at least a college education (70.8%). The most common comorbid conditions were high blood pressure (10.0%), thyroid disease (4.6%), diabetes without complications (4.6%), congestive heart failure (3.9%) and rheumatologic conditions (3.9%). While over 65% were full time employed at the time of MBC diagnosis, only 26% were at the time they completed the survey. 69% were currently taking a trastuzumab containing regimen, commonly with another medication. Frequently used medications included lapatinib and paclitaxel. Symptoms reported as frequently bothersome by at least 20% of women were: tiredness (52%), decreased sexual interest (50%), difficulty sleeping (39%), worry (39%), joint/ muscle pain (34%), difficulty concentrating (27%), alopecia (24%), low back pain (23%), depressed mood (22%), constipation (20%), and tingling of hands or feet (20%). Despite their disease, these women expressed high levels of satisfaction with their lives and relationships (with family, friends, and other women with MBC), but were less satisfied with their employment and their feeling about the future. They expressed higher levels of burden due to pain/discomfort and anxiety/depression than due to usual activities, self-care, and mobility. Fewer than 10% had discussed palliative care options with their doctor. Conclusions: This community survey of women with HER2+ MBC provides valuable insights into their demographics, work status, treatment, and symptom burden." @default.
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• W2563490400 date "2011-05-20" @default.
• W2563490400 modified "2023-09-27" @default.
• W2563490400 title "Assessment of burden of illness in women with HER2+ metastatic breast cancer: Findings from a community web-based survey." @default.
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• W2563490400 doi "https://doi.org/10.1200/jco.2011.29.15_suppl.e11121" @default.
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