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- W2563749819 endingPage "510" @default.
- W2563749819 startingPage "502" @default.
- W2563749819 abstract "This laboratory has studied the intracellular actions of angiotensin II and other signaling proteins that can act in the intracellular space-peptides/proteins we have called intracrines. Moreover, we have suggested that general principles of intracrine action exist and can help explain the progression of some chronic degenerative diseases such as diabetic nephropathy and congestive heart failure. Here, a similar analysis is carried out in the case of age-related macular degeneration. We propose that intracrine mechanisms are operative in this disorder. In particular, we hypothesize that intracrine loops involving renin, angiotensin II, transforming growth factor-beta, vascular endothelial growth factor, bone morphogenetic protein-4, and p53, among other factors, are involved. If this analysis is correct, it suggests a commonality of mechanism linking chronic progressive renal diseases, congestive heart failure, and macular degeneration." @default.
- W2563749819 created "2017-01-06" @default.
- W2563749819 creator A5026727208 @default.
- W2563749819 date "2016-01-01" @default.
- W2563749819 modified "2023-09-23" @default.
- W2563749819 title "Age-Related Macular Degeneration and Intracrine Biology: An Hypothesis." @default.
- W2563749819 cites W1496397347 @default.
- W2563749819 cites W1497853576 @default.
- W2563749819 cites W1503388237 @default.
- W2563749819 cites W1534760353 @default.
- W2563749819 cites W1960434785 @default.
- W2563749819 cites W1960536870 @default.
- W2563749819 cites W1965732954 @default.
- W2563749819 cites W1970158133 @default.
- W2563749819 cites W1978468783 @default.
- W2563749819 cites W1978535164 @default.
- W2563749819 cites W1980736324 @default.
- W2563749819 cites W1981168110 @default.
- W2563749819 cites W1981809254 @default.
- W2563749819 cites W1983991762 @default.
- W2563749819 cites W1986403962 @default.
- W2563749819 cites W1991354906 @default.
- W2563749819 cites W1992308750 @default.
- W2563749819 cites W1999315076 @default.
- W2563749819 cites W1999550698 @default.
- W2563749819 cites W2000958693 @default.
- W2563749819 cites W2001799682 @default.
- W2563749819 cites W2003545373 @default.
- W2563749819 cites W2007273526 @default.
- W2563749819 cites W2007917457 @default.
- W2563749819 cites W2008388660 @default.
- W2563749819 cites W2009758003 @default.
- W2563749819 cites W2019733335 @default.
- W2563749819 cites W2029452873 @default.
- W2563749819 cites W2029685980 @default.
- W2563749819 cites W2031032144 @default.
- W2563749819 cites W2031099464 @default.
- W2563749819 cites W2033618430 @default.
- W2563749819 cites W2034821844 @default.
- W2563749819 cites W2035162736 @default.
- W2563749819 cites W2041916290 @default.
- W2563749819 cites W2050048832 @default.
- W2563749819 cites W2051943841 @default.
- W2563749819 cites W2053713685 @default.
- W2563749819 cites W2057620757 @default.
- W2563749819 cites W2057760874 @default.
- W2563749819 cites W2060575303 @default.
- W2563749819 cites W2061673720 @default.
- W2563749819 cites W2061988509 @default.
- W2563749819 cites W2065535426 @default.
- W2563749819 cites W2066507973 @default.
- W2563749819 cites W2070964261 @default.
- W2563749819 cites W2071255261 @default.
- W2563749819 cites W2075582632 @default.
- W2563749819 cites W2075865306 @default.
- W2563749819 cites W2083021412 @default.
- W2563749819 cites W2083578374 @default.
- W2563749819 cites W2083985618 @default.
- W2563749819 cites W2086324825 @default.
- W2563749819 cites W2091429537 @default.
- W2563749819 cites W2092319843 @default.
- W2563749819 cites W2096069659 @default.
- W2563749819 cites W2098258719 @default.
- W2563749819 cites W2100462890 @default.
- W2563749819 cites W2109151256 @default.
- W2563749819 cites W2118681831 @default.
- W2563749819 cites W2124490881 @default.
- W2563749819 cites W2126739807 @default.
- W2563749819 cites W2130855066 @default.
- W2563749819 cites W2131939677 @default.
- W2563749819 cites W2132943628 @default.
- W2563749819 cites W2138104864 @default.
- W2563749819 cites W2140506790 @default.
- W2563749819 cites W2154462339 @default.
- W2563749819 cites W2156403998 @default.
- W2563749819 cites W2156776533 @default.
- W2563749819 cites W2157752616 @default.
- W2563749819 cites W2159579113 @default.
- W2563749819 cites W2159773815 @default.
- W2563749819 cites W2160179291 @default.
- W2563749819 cites W2161396131 @default.
- W2563749819 cites W2161436007 @default.
- W2563749819 cites W2167674301 @default.
- W2563749819 cites W2168081842 @default.
- W2563749819 cites W2224204524 @default.
- W2563749819 cites W2228317445 @default.
- W2563749819 cites W2256799488 @default.
- W2563749819 cites W2304129453 @default.
- W2563749819 cites W2305682938 @default.
- W2563749819 cites W2336380483 @default.
- W2563749819 cites W2387311239 @default.
- W2563749819 cites W2400343141 @default.
- W2563749819 cites W2411347995 @default.
- W2563749819 cites W2418477171 @default.
- W2563749819 cites W256992154 @default.
- W2563749819 cites W289240186 @default.
- W2563749819 cites W60487933 @default.
- W2563749819 cites W86264492 @default.