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- W2563948320 abstract "Objective: to determine and compare parameters of diagnostic value of immunological tests in the diagnosis of tuberculosis in patients with HIV infection. Materials and methods: During 2013-2014 years9 cohort study was conducted. Were examined 88 patients with HIV infection and healthy people (control group – n=18). Diagnostic complex included: QuantiFERON®-TB Gold (QFT), TB.SPOT, X-ray, sputum smear examination, cultural and PCR methods. Patients were divided into two groups: I- HIV(n=41) and II -HIV + TB(n = 43). Results: Data of immunological study are presented in table. Significant results were obtained in group II with a positive test result for both TB.SPOT, and QFT. RR for positive result of TB.SPOT (RR = 3.3) in group II was twice higher than QFT (RR = 2.5). In group I, RR of positive result for TB.SPOT (RR = 0,3) was comparable with QFT (RR = 0,2). Indicators of the diagnostic significance of TB.SPOT (Se = 90.0%, Sp = 88.2%, DV = 89.1%) and QFT (Se = 82.9%, Sp = 82.4%, DV= 82.7%) were comparable. Conclusions: Results of TB.SPOT was slightly higher than QFT in the diagnosis of tuberculosis infection in patients with HIV. Risk factor for a positive result TB.SPOT two times higher than the figure QFT, which significantly increases the ability to detect latent TB infection in patients with HIV." @default.
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- W2563948320 date "2015-09-01" @default.
- W2563948320 modified "2023-09-26" @default.
- W2563948320 title "The value of immunological methods in the diagnosis of tuberculosis in patients with HIV" @default.
- W2563948320 doi "https://doi.org/10.1183/13993003.congress-2015.pa2981" @default.
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