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- W2563956285 abstract "The Croatian Island of Rab is situated in the Northern Adriatic Sea. Evidence of human presence are seen from the Neolithic period and ever since this Island has been inhabitated by many ethnically different populations. After Illyrians and Romans, one of the most genetically and historically important periods was arrivals of Slavic tribes from 8th until 10th century. Here we present the evidence of high impact of the genetic drift on the genetic diversity and structure of the contemporary Rab Islanders. Analysis of mitochondrial DNA haplogroups of 163 autochthonous inhabitants from 5 settlements revealed relatively high level of haplogroup and haplotype diversity in the overall sample due to dynamic gene flow throughout history. On the other hand, only four haplogroups (H6, HV, J1c and U4) encompass more than one half of total maternal gene pool of this Island. Even so, every fourth contemporary Islander has one particular haplotype of U4d2 haplogroup. This is so far the most frequent finding of this haplogroup ever reported in any population (24.5 %). One possible explanation of such high deviation from average European frequency could be due to several epidemics of plague in 15th and 16th century when a vast majority of population died, in some cases almost 90 % of some settlements were devastated. The results of this study gave insight into microevolutionary processes that shaped the current maternal gene pool of this northern Adriatic Island." @default.
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- W2563956285 date "2013-01-01" @default.
- W2563956285 modified "2023-09-28" @default.
- W2563956285 title "High impact of genetic drift on the isolated population of Rab Island – evidence from mitochondrial DNA diversity" @default.
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