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- W2564134680 abstract "Celiac disease (CeD) and inflammatory bowel disease (IBD) are chronic inflammatory diseases affecting the gastrointestinal tract. They share certain characteristics, including autoimmune features, the presence of both gastrointestinal and systemic clinical symptoms, and pathogenic contributions by genetic and environmental factors. However, there are several stark differences that must be appreciated. The immunogenic mechanisms of the two diseases are unique, with differing contributions by the innate and adaptive immune responses. Histologically, CeD is distinct from IBD, which is useful diagnostically as well as for gaining insight into disease mechanisms. Lastly, the role of diagnostic laboratory testing, both serologic and genetic, differs greatly between CeD and IBD. The purpose of this chapter is to provide a summary of what is currently known about the pathogenesis, epidemiology, clinical presentation, and diagnostic testing for CeD and IBD." @default.
- W2564134680 created "2017-01-06" @default.
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- W2564134680 date "2016-01-27" @default.
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- W2564134680 title "Celiac Disease and Inflammatory Bowel Disease" @default.
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- W2564134680 doi "https://doi.org/10.1128/9781555818722.ch103" @default.
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