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- W2564165694 abstract "Recently Romero Lauro et al. (2014) published the results of a study (‘TDCS increases cortical excitability: Direct evidence from TMS-EEG’) demonstrating altered cortical excitability following tDCS, using a combination of TMS and EEG to assess excitability before, during, and after tDCS. One of their goals was to assess not just whether cortical excitability was altered by tDCS, but whether brain areas that were not directly stimulated by tDCS also exhibited altered excitability. This speaks to the question of whether indirect effects of tDCS occur in regions connected to the directly stimulated region. In other words, Romero Lauro et al.'s research attempts to answer whether tDCS at one location affects activity across diverse regions in the brain, through spreading activation via connected regions. Their results indicated that activity recorded from the scalp over nonstimulated clusters differed following tDCS, so they concluded that tDCS shows spreading activation changes to non-stimulated brain regions. This study is the first to explore the effect of tDCS on cortical excitability with TMS-EEG outside the motor system, and as such we agree that this is a novel and interesting study with excellent experimental design. However, we are concerned that a potentially significant confound was not addressed with enough clarity for readers without significant technical expertise in EEG to understand the limitation. Specifically, the manner in which changes in excitability were assessed in non-stimulated regions from pre to post and be-" @default.
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- W2564165694 date "2014-01-01" @default.
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- W2564165694 title "Commentary regarding: TDCS increases cortical excitability: Direct evidence from TMS-EEG" @default.
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