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- W2564206783 abstract "Objective: To evaluate the age-specific mortality in a national TB cohort, and to estimate relative age-specific mortality compared with matched controls, in a retrospective case-control study. Methods: Using Danish National Patient Registry, we retrospectively identified TB-patients between 1998-2010. They were matched to controls by age, gender, civil status and geography. Mortality data were obtained from Danish Civil Registration System. We calculated age-specific hazard ratio and cumulative survival function, adjusting for varying follow-up, distributing. Results: 6713 cases and 28217 controls were followed for max. 12 (span: 0-12) years. Mortality was higher for cases than controls in all age groups, and significantly so for age groups above 20 years, peaking at a Hazard Ratio of 8.7 (95% CI: 5.53;16.69) in the 30-39 years age. Absolute difference in mortality increased with older age. Conclusion: Cumulative mortality of TB-patients is significantly inferior to matched controls. While the difference in survival is substantial among elderly patients, a high relative risk of dying is particularly of concern among young and middle-aged adult TB patients." @default.
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- W2564206783 date "2015-09-01" @default.
- W2564206783 modified "2023-09-27" @default.
- W2564206783 title "Age-specific mortality among tuberculosis-patients in Denmark 1998-2010" @default.
- W2564206783 doi "https://doi.org/10.1183/13993003.congress-2015.pa2712" @default.
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