Matches in SemOpenAlex for { <https://semopenalex.org/work/W2564389970> ?p ?o ?g. }
- W2564389970 endingPage "1261" @default.
- W2564389970 startingPage "1253" @default.
- W2564389970 abstract "(i) to evaluate a novel hybrid near-infrared fluorescence—intravascular ultrasound (NIRF-IVUS) system in coronary and peripheral swine arteries in vivo; (ii) to assess simultaneous quantitative biological and morphological aspects of arterial disease. Two 9F/15MHz peripheral and 4.5F/40MHz coronary near-infrared fluorescence (NIRF)-IVUS catheters were engineered to enable accurate co-registrtation of biological and morphological readings simultaneously in vivo. A correction algorithm utilizing IVUS information was developed to account for the distance-related fluorescence attenuation due to through-blood imaging. Corrected NIRF (cNIRF)-IVUS was applied for in vivo imaging of angioplasty-induced vascular injury in swine peripheral arteries and experimental fibrin deposition on coronary artery stents, and of atheroma in a rabbit aorta, revealing feasibility to intravascularly assay plaque structure and inflammation. The addition of ICG-enhanced NIRF assessment improved the detection of angioplasty-induced endothelial damage compared to standalone IVUS. In addition, NIRF detection of coronary stent fibrin by in vivo cNIRF-IVUS imaging illuminated stent pathobiology that was concealed on standalone IVUS. Fluorescence reflectance imaging and microscopy of resected tissues corroborated the in vivo findings. Integrated cNIRF-IVUS enables simultaneous co-registered through-blood imaging of disease related morphological and biological alterations in coronary and peripheral arteries in vivo. Clinical translation of cNIRF-IVUS may significantly enhance knowledge of arterial pathobiology, leading to improvements in clinical diagnosis and prognosis, and helps to guide the development of new therapeutic approaches for arterial diseases." @default.
- W2564389970 created "2017-01-06" @default.
- W2564389970 creator A5005270186 @default.
- W2564389970 creator A5008102023 @default.
- W2564389970 creator A5010718958 @default.
- W2564389970 creator A5011207594 @default.
- W2564389970 creator A5017027780 @default.
- W2564389970 creator A5017046939 @default.
- W2564389970 creator A5025682028 @default.
- W2564389970 creator A5035255903 @default.
- W2564389970 creator A5035480544 @default.
- W2564389970 creator A5036467116 @default.
- W2564389970 creator A5059881887 @default.
- W2564389970 creator A5062776420 @default.
- W2564389970 creator A5086387340 @default.
- W2564389970 date "2016-12-21" @default.
- W2564389970 modified "2023-10-17" @default.
- W2564389970 title "Quantitative intravascular biological fluorescence-ultrasound imaging of coronary and peripheral arteries in vivo" @default.
- W2564389970 cites W1527614413 @default.
- W2564389970 cites W1889220474 @default.
- W2564389970 cites W1956305767 @default.
- W2564389970 cites W1977756163 @default.
- W2564389970 cites W1986846490 @default.
- W2564389970 cites W1989163359 @default.
- W2564389970 cites W2003383009 @default.
- W2564389970 cites W2012079485 @default.
- W2564389970 cites W2017732091 @default.
- W2564389970 cites W2020466729 @default.
- W2564389970 cites W2028446046 @default.
- W2564389970 cites W2033896075 @default.
- W2564389970 cites W2043798557 @default.
- W2564389970 cites W2055029456 @default.
- W2564389970 cites W2058725029 @default.
- W2564389970 cites W2072032492 @default.
- W2564389970 cites W2087447022 @default.
- W2564389970 cites W2090382325 @default.
- W2564389970 cites W2120688065 @default.
- W2564389970 cites W2123725941 @default.
- W2564389970 cites W2134254671 @default.
- W2564389970 cites W2146228563 @default.
- W2564389970 cites W2147906777 @default.
- W2564389970 cites W2161000713 @default.
- W2564389970 cites W2167761943 @default.
- W2564389970 cites W2212419929 @default.
- W2564389970 cites W2240104466 @default.
- W2564389970 cites W2344341837 @default.
- W2564389970 cites W2470507429 @default.
- W2564389970 cites W2515748364 @default.
- W2564389970 doi "https://doi.org/10.1093/ehjci/jew222" @default.
- W2564389970 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/5837649" @default.
- W2564389970 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/28031233" @default.
- W2564389970 hasPublicationYear "2016" @default.
- W2564389970 type Work @default.
- W2564389970 sameAs 2564389970 @default.
- W2564389970 citedByCount "25" @default.
- W2564389970 countsByYear W25643899702017 @default.
- W2564389970 countsByYear W25643899702018 @default.
- W2564389970 countsByYear W25643899702019 @default.
- W2564389970 countsByYear W25643899702020 @default.
- W2564389970 countsByYear W25643899702021 @default.
- W2564389970 countsByYear W25643899702022 @default.
- W2564389970 countsByYear W25643899702023 @default.
- W2564389970 crossrefType "journal-article" @default.
- W2564389970 hasAuthorship W2564389970A5005270186 @default.
- W2564389970 hasAuthorship W2564389970A5008102023 @default.
- W2564389970 hasAuthorship W2564389970A5010718958 @default.
- W2564389970 hasAuthorship W2564389970A5011207594 @default.
- W2564389970 hasAuthorship W2564389970A5017027780 @default.
- W2564389970 hasAuthorship W2564389970A5017046939 @default.
- W2564389970 hasAuthorship W2564389970A5025682028 @default.
- W2564389970 hasAuthorship W2564389970A5035255903 @default.
- W2564389970 hasAuthorship W2564389970A5035480544 @default.
- W2564389970 hasAuthorship W2564389970A5036467116 @default.
- W2564389970 hasAuthorship W2564389970A5059881887 @default.
- W2564389970 hasAuthorship W2564389970A5062776420 @default.
- W2564389970 hasAuthorship W2564389970A5086387340 @default.
- W2564389970 hasBestOaLocation W25643899701 @default.
- W2564389970 hasConcept C126322002 @default.
- W2564389970 hasConcept C126838900 @default.
- W2564389970 hasConcept C136229726 @default.
- W2564389970 hasConcept C142724271 @default.
- W2564389970 hasConcept C150903083 @default.
- W2564389970 hasConcept C164705383 @default.
- W2564389970 hasConcept C203014093 @default.
- W2564389970 hasConcept C207001950 @default.
- W2564389970 hasConcept C2776820930 @default.
- W2564389970 hasConcept C2776931568 @default.
- W2564389970 hasConcept C2778213512 @default.
- W2564389970 hasConcept C2778742706 @default.
- W2564389970 hasConcept C2779318932 @default.
- W2564389970 hasConcept C2780326628 @default.
- W2564389970 hasConcept C46762472 @default.
- W2564389970 hasConcept C54173615 @default.
- W2564389970 hasConcept C71924100 @default.
- W2564389970 hasConcept C86803240 @default.
- W2564389970 hasConceptScore W2564389970C126322002 @default.
- W2564389970 hasConceptScore W2564389970C126838900 @default.
- W2564389970 hasConceptScore W2564389970C136229726 @default.