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- W2564432972 abstract "It is well established that oxidative stress is involved in the pathogenesis of hypertension. With regard to oxidative stress, however, much attention has been focused on vascular damage in the process of hypertension. In consecutive studies, we have been investigating the role of brain oxidative stress in the central nervous system control of blood pressure. Indeed, we found that oxidative stress is increased in the brain stem, thereby activating the sympathetic nervous system, leading to hypertension. In this chapter, we describe our series of consecutive studies regarding this issue and supporting reports from other laboratories. Because of the importance of sympathetic activation for hypertensive vascular damage, our concepts not only of the pathogenesis but also the therapeutic aspects of hypertension are worthy of attention." @default.
- W2564432972 created "2017-01-06" @default.
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- W2564432972 date "2016-12-23" @default.
- W2564432972 modified "2023-09-27" @default.
- W2564432972 title "Oxidative Stress and Central Regulation of Blood Pressure" @default.
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- W2564432972 doi "https://doi.org/10.1007/978-1-4899-7693-2_5" @default.
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