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- W2564482008 abstract "One-third of epilepsy patients develop drug resistance, and half of them can benefit from the surgical removal of epileptic focus (EF). Neuromodulation represents the only hope to ameliorate the quality of life of the remaining patients [ [1] Lee K.J. Shon Y.M. Cho C.B. Long-term outcome of anterior thalamic nucleus stimulation for intractable epilepsy. Stereotact Funct Neurosurg. 2012; 90: 379-385 Crossref PubMed Scopus (83) Google Scholar ]. Cathodal transcranial direct current stimulation (ctDCS) is a techniques able to non-invasively inhibit cortical excitability [ [2] Liebetanz D. Nitsche M.A. Tergau F. Paulus W. Pharmacological approach to the mechanisms of transcranial DC-stimulation-induced after-effects of human motor cortex excitability. Brain [Internet]. 2002; 125: 2238-2247 Crossref Scopus (1027) Google Scholar ], which is abnormally increased in epilepsy [ [3] Hamer H.M. Reis J. Mueller H.-H. Knake S. Overhof M. Oertel W.H. et al. Motor cortex excitability in focal epilepsies not including the primary motor area–a TMS study. Brain [Internet]. 2005; 128: 811-818 Crossref Scopus (90) Google Scholar ]. Preliminary results of ctDCS of Epileptic focus (EF) of focal drug-resistant epilepsy (DRE) are promising [ [4] Tekturk P. Erdogan E.T. Kurt A. Vanli-yavuz E.N. Ekizoglu E. Kocagoncu E. et al. The effect of transcranial direct current stimulation on seizure frequency of patients with mesial temporal lobe epilepsy with hippocampal sclerosis. Clin Neurol Neurosurg. 2016; 149: 27-32 Crossref PubMed Scopus (41) Google Scholar ], but several technical issues could be optimized to achieve a clinically relevant effect." @default.
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- W2564482008 date "2017-03-01" @default.
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- W2564482008 title "Cathodal transcranial direct current stimulation reduces seizure frequency in adults with drug-resistant temporal lobe epilepsy: A sham controlled study" @default.
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- W2564482008 doi "https://doi.org/10.1016/j.brs.2016.12.005" @default.
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