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- W2564586087 abstract "To develop a survival score for patients receiving whole-brain irradiation (WBI) alone for cerebral metastases from melanoma.Forty-five patients who met the required criteria were included. WBI doses had to be >30 Gy. Six variables were analyzed: age, gender, Karnofsky performance score (KPS), number of cerebral metastases, extracranial metastatic spread and interval from diagnosis of melanoma until WBI. In order to estimate patients' survival scores, variables showing at least a trend (p<0.06) on multivariate analysis were considered. One point was assigned to each variable correlating with better survival rates and zero points to those correlating with worse survival rates.By multivariate analysis, age (p=0.002) achieved significance and KPS (p=0.056) showed a trend. Patients' survival scores were obtained by adding zero or one point from each variable and resulted in three groups of 0, 1 or 2 points. The median survival times of these groups were one, four and ten months (p<0.0001).A survival score was developed for patients assigned to WBI alone for cerebral metastases from melanoma. This new instrument may facilitate the decision for the appropriate WBI-program." @default.
- W2564586087 created "2017-01-06" @default.
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- W2564586087 date "2017-01-01" @default.
- W2564586087 modified "2023-09-23" @default.
- W2564586087 title "Development of a Survival Score for Patients with Cerebral Metastases from Melanoma" @default.
- W2564586087 doi "https://doi.org/10.21873/anticanres.11314" @default.
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- W2564586087 hasPublicationYear "2017" @default.
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