Matches in SemOpenAlex for { <https://semopenalex.org/work/W2564725098> ?p ?o ?g. }
Showing items 1 to 67 of
67
with 100 items per page.
- W2564725098 abstract "Introduction: Bevacizumab is an antiangiogenic drug used in the therapy of numerous solid tumours including colorectal adenocarcinoma. The efficacy and safety of bevacizumab has been demonstrated in many multicenter clinical trials. The scope of this paper is to analyze the safety profile of bevacizumab in patients with stage IV colorectal cancer. Aim of the study: Analysis of toxicity and safety of the treatment with bevacizumab patients with colorectal cancer in the metastatic stage. Material and methods: Retrospective analysis of medical records of 42 patients with advanced colorectal cancer treated in the Department of Systemic and Generalized Malignancies, Maria Skłodowska-Curie Memorial Institute of Oncology, Kraków Branch, in the period 2007–2014. Results: The median time of treatment with bevacizumab was 6 months. The median duration of progression-free survival (PFS) was 8.5 months. Toxicity of treatment with bevacizumab affected 43 percent of patients. The most common adverse events observed was hypertension and bleeding. In 6 patients (14.3%) the treatment with bevacizumab was interrupted due to adverse events (thromboembolic events, bleeding and gastrointestinal perforation). Conclusions: Bevacizumab is a safe therapeutic option in patients with metastatic colorectal cancer, provided that patients are provided close oncological and general medical monitoring." @default.
- W2564725098 created "2017-01-06" @default.
- W2564725098 creator A5014007160 @default.
- W2564725098 creator A5024324737 @default.
- W2564725098 creator A5045257171 @default.
- W2564725098 creator A5073181265 @default.
- W2564725098 date "2016-12-30" @default.
- W2564725098 modified "2023-10-02" @default.
- W2564725098 title "Complications of palliative antiangiogenic therapy in patients with colorectal cancer" @default.
- W2564725098 cites W1586129343 @default.
- W2564725098 cites W1592045168 @default.
- W2564725098 cites W1606278307 @default.
- W2564725098 cites W1684140257 @default.
- W2564725098 cites W1855067957 @default.
- W2564725098 cites W1872181102 @default.
- W2564725098 cites W1969979925 @default.
- W2564725098 cites W1999223106 @default.
- W2564725098 cites W2002986768 @default.
- W2564725098 cites W2014329705 @default.
- W2564725098 cites W2060447671 @default.
- W2564725098 cites W2096134439 @default.
- W2564725098 cites W2102147859 @default.
- W2564725098 cites W2104569020 @default.
- W2564725098 cites W2106130415 @default.
- W2564725098 cites W2111790572 @default.
- W2564725098 cites W2121409808 @default.
- W2564725098 cites W2121785313 @default.
- W2564725098 cites W2123604415 @default.
- W2564725098 cites W2125447919 @default.
- W2564725098 cites W2143743735 @default.
- W2564725098 cites W2146916102 @default.
- W2564725098 cites W2157769714 @default.
- W2564725098 cites W2162731664 @default.
- W2564725098 cites W2164621617 @default.
- W2564725098 cites W2165741055 @default.
- W2564725098 cites W2169932958 @default.
- W2564725098 doi "https://doi.org/10.5604/01.3001.0009.5069" @default.
- W2564725098 hasPublicationYear "2016" @default.
- W2564725098 type Work @default.
- W2564725098 sameAs 2564725098 @default.
- W2564725098 citedByCount "2" @default.
- W2564725098 countsByYear W25647250982017 @default.
- W2564725098 countsByYear W25647250982018 @default.
- W2564725098 crossrefType "journal-article" @default.
- W2564725098 hasAuthorship W2564725098A5014007160 @default.
- W2564725098 hasAuthorship W2564725098A5024324737 @default.
- W2564725098 hasAuthorship W2564725098A5045257171 @default.
- W2564725098 hasAuthorship W2564725098A5073181265 @default.
- W2564725098 hasConcept C121608353 @default.
- W2564725098 hasConcept C126322002 @default.
- W2564725098 hasConcept C143998085 @default.
- W2564725098 hasConcept C2992356464 @default.
- W2564725098 hasConcept C526805850 @default.
- W2564725098 hasConcept C71924100 @default.
- W2564725098 hasConceptScore W2564725098C121608353 @default.
- W2564725098 hasConceptScore W2564725098C126322002 @default.
- W2564725098 hasConceptScore W2564725098C143998085 @default.
- W2564725098 hasConceptScore W2564725098C2992356464 @default.
- W2564725098 hasConceptScore W2564725098C526805850 @default.
- W2564725098 hasConceptScore W2564725098C71924100 @default.
- W2564725098 hasLocation W25647250981 @default.
- W2564725098 hasOpenAccess W2564725098 @default.
- W2564725098 hasPrimaryLocation W25647250981 @default.
- W2564725098 isParatext "false" @default.
- W2564725098 isRetracted "false" @default.
- W2564725098 magId "2564725098" @default.
- W2564725098 workType "article" @default.