Matches in SemOpenAlex for { <https://semopenalex.org/work/W2564776656> ?p ?o ?g. }
Showing items 1 to 65 of
65
with 100 items per page.
- W2564776656 endingPage "583" @default.
- W2564776656 startingPage "578" @default.
- W2564776656 abstract "The aim of the study was to investigate a relationship between frequency of exacerbations of chronic obstructive pulmonary disease (COPD) and renal dysfunction in patients with COPD. Methods. We examined 200 patients with COPD diagnosed according to GOLD, 2015. The patients were divided into 4 groups according to a rate of exacerbations of COPD and severity of symptoms. A and B groups had rare exacerbations (≤ 1 per year), C and D groups had frequent exacerbations (≥ 2 per year). Patients in A and D groups experienced less symptoms of COPD and patients in B and C groups had more symptoms. To investigate the renal function, glomerular filtration rate (GFR) was calculated in all patients twice during 6 months using the СKDEPI formula; also, albuminuria (AU) was measured and renal ultrasonography was performed. Results. Pathological kidney disorders were found in 106 patients (53%). Positive correlations were found between the renal resistance index (RI) and FEV1 and between RI and age of the patients. Inverse correlations were found between FEV1 and increased AU and between frequency of exacerbations and AU. Chronic kidney disease (CKD) was diagnosed in 105 patients with COPD (52.5%). A persistent decrease in GFR < 60 ml/min/1.73m2 was revealed in 74 patients with COPD (37.0%). Stage I – II CKD was diagnosed in 31 of 126 COPD patients with normal or slightly decreased GFR (15.5%). Thus, stage I CKD was diagnosed in 13 patients with COPD (6.5%), stage II CKD was diagnosed in 18 patients (9.0%), stage III A CKD was diagnosed in 54 patients (27.0%), stage III B CKD was diagnosed in 16 patients (8.0%), and stage IV CKD was diagnosed in 4 patients (2.0%). Conclusions. CKD was diagnosed in 52.5% of patients with COPD. The prevalence of CKD was significantly higher in C and D groups. Stage III – IV CKD was diagnosed in patients with frequent exacerbations of COPD significantly more often. Clinically significant AU could be related to higher cardiovascular risk. Renal dysfunction in COPD patients could be due to endothelial dysfunction and systemic effects of COPD." @default.
- W2564776656 created "2017-01-06" @default.
- W2564776656 creator A5058515480 @default.
- W2564776656 creator A5079074912 @default.
- W2564776656 date "2016-12-20" @default.
- W2564776656 modified "2023-10-18" @default.
- W2564776656 title "CHRONIC KIDNEY DISEASE IN PATIENTS WITH CHRONIC OBSTRUCTIVE PULMONARY DISEASE: A ROLE OF EXACERBATIONS" @default.
- W2564776656 doi "https://doi.org/10.18093/0869-0189-2016-26-5-578-583" @default.
- W2564776656 hasPublicationYear "2016" @default.
- W2564776656 type Work @default.
- W2564776656 sameAs 2564776656 @default.
- W2564776656 citedByCount "7" @default.
- W2564776656 countsByYear W25647766562018 @default.
- W2564776656 countsByYear W25647766562019 @default.
- W2564776656 countsByYear W25647766562020 @default.
- W2564776656 countsByYear W25647766562021 @default.
- W2564776656 crossrefType "journal-article" @default.
- W2564776656 hasAuthorship W2564776656A5058515480 @default.
- W2564776656 hasAuthorship W2564776656A5079074912 @default.
- W2564776656 hasBestOaLocation W25647766561 @default.
- W2564776656 hasConcept C126322002 @default.
- W2564776656 hasConcept C146357865 @default.
- W2564776656 hasConcept C151730666 @default.
- W2564776656 hasConcept C159641895 @default.
- W2564776656 hasConcept C207886595 @default.
- W2564776656 hasConcept C2776174234 @default.
- W2564776656 hasConcept C2776780178 @default.
- W2564776656 hasConcept C2777014857 @default.
- W2564776656 hasConcept C2778653478 @default.
- W2564776656 hasConcept C71924100 @default.
- W2564776656 hasConcept C86803240 @default.
- W2564776656 hasConcept C90924648 @default.
- W2564776656 hasConceptScore W2564776656C126322002 @default.
- W2564776656 hasConceptScore W2564776656C146357865 @default.
- W2564776656 hasConceptScore W2564776656C151730666 @default.
- W2564776656 hasConceptScore W2564776656C159641895 @default.
- W2564776656 hasConceptScore W2564776656C207886595 @default.
- W2564776656 hasConceptScore W2564776656C2776174234 @default.
- W2564776656 hasConceptScore W2564776656C2776780178 @default.
- W2564776656 hasConceptScore W2564776656C2777014857 @default.
- W2564776656 hasConceptScore W2564776656C2778653478 @default.
- W2564776656 hasConceptScore W2564776656C71924100 @default.
- W2564776656 hasConceptScore W2564776656C86803240 @default.
- W2564776656 hasConceptScore W2564776656C90924648 @default.
- W2564776656 hasIssue "5" @default.
- W2564776656 hasLocation W25647766561 @default.
- W2564776656 hasOpenAccess W2564776656 @default.
- W2564776656 hasPrimaryLocation W25647766561 @default.
- W2564776656 hasRelatedWork W1964141021 @default.
- W2564776656 hasRelatedWork W1993867854 @default.
- W2564776656 hasRelatedWork W2018901137 @default.
- W2564776656 hasRelatedWork W2113389249 @default.
- W2564776656 hasRelatedWork W2125575764 @default.
- W2564776656 hasRelatedWork W2151509478 @default.
- W2564776656 hasRelatedWork W2494555525 @default.
- W2564776656 hasRelatedWork W2554684418 @default.
- W2564776656 hasRelatedWork W4236593106 @default.
- W2564776656 hasRelatedWork W4315631231 @default.
- W2564776656 hasVolume "26" @default.
- W2564776656 isParatext "false" @default.
- W2564776656 isRetracted "false" @default.
- W2564776656 magId "2564776656" @default.
- W2564776656 workType "article" @default.