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- W2564907072 abstract "Aim: To assess the safety and efficacy of cell therapies for chronic stroke. Methodology: Five databases were searched for treatments administered >90 days post-stroke. Reporting quality, adherence to research guidelines, treatment safety (risk ratios/pooled incidence rates) and neurological/functional efficacy (Hedge’s g) were all evaluated. Results: Twenty-three studies examined 17 treatments. Reporting quality scores were medium to high, but adherence to recommended guidelines was lower. Three treatments resulted in serious adverse events; four improved outcomes more than standard care. However, many studies were under-powered and individual patients varied in their response to some treatments. Conclusion: Preliminary findings suggest that some cell therapies may be relatively safe and effective, but larger double-blinded placebo-controlled studies are needed to establish the long-term risks and benefits." @default.
- W2564907072 created "2017-01-06" @default.
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- W2564907072 date "2017-01-01" @default.
- W2564907072 modified "2023-09-25" @default.
- W2564907072 title "Cell therapies administered in the chronic phase after stroke: a meta-analysis examining safety and efficacy" @default.
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- W2564907072 doi "https://doi.org/10.2217/rme-2016-0082" @default.
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