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- W2565024105 abstract "Abstract Increased serum bilirubin level is a widely used diagnostic marker for hepatic illnesses. Nevertheless, mild elevation of unconjugated serum bilirubin (such as in Gilbert syndrome) has been recently demonstrated to correlate with low risk of chronic inflammatory and/or oxidative stress‐mediated diseases. In accord, a low serum bilirubin level has emerged as an important predisposing factor or a biomarker of these pathologic conditions including cardiovascular, tumour, and possibly neurodegenerative diseases. Bilirubin possesses multiple biological actions with interaction in a complex network of enzymatic and signalling pathways. The fact that the liver is the main organ controlling the bioavailability of bilirubin emphasizes the central role of this organ in human health." @default.
- W2565024105 created "2017-01-06" @default.
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- W2565024105 date "2017-01-11" @default.
- W2565024105 modified "2023-10-13" @default.
- W2565024105 title "The molecular basis of jaundice: An old symptom revisited" @default.
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- W2565024105 doi "https://doi.org/10.1111/liv.13351" @default.
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