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- W2565353089 abstract "This chapter considers the central organization of sexual function, the regulation of the hypothalamo-pituitary-testicular (HPT) axis, the role of androgens in sexual function, and finally the different pathologies of the endocrine system that impact on male sexual function. Male sexual dysfunction (MSD) encompasses disturbances of libido, erectile function, ejaculation, orgasm, and detumescence, and affects up to 10% of middle-aged or older men. Endocrine disorders should be considered in this context, although non-endocrine factors, particularly psychosexual ones, may be more important. Of all hormonal disorders, diabetes mellitus (DM) is, worldwide, the most common and important cause of organic erectile dysfunction (ED), increasing the risk three-fold compared to men without a history of DM. By comparison, male hypogonadism, a clinical syndrome resulting from subphysiological testosterone levels due to a perturbation of the HPT axis at one or more levels, is a far less common cause of sexual dysfunction." @default.
- W2565353089 created "2017-01-06" @default.
- W2565353089 creator A5058902714 @default.
- W2565353089 creator A5073255482 @default.
- W2565353089 date "2016-12-16" @default.
- W2565353089 modified "2023-10-17" @default.
- W2565353089 title "Endocrinology of male sexual dysfunction" @default.
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- W2565353089 doi "https://doi.org/10.1002/9781118746509.ch5" @default.
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