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- W2565612004 abstract "Drosophila is a powerful model to study human diseases thanks to its genetic tools and ease of screening. Human genes can be expressed in targeted organs and their toxicity assessed on easily scorable external phenotypes that can be used as readout to perform genetic screen of toxicity modifiers. In this chapter, I describe how to express human Tau protein in the Drosophila eye, assess protein expression by western blot, assess Tau toxicity by quantifying the size of the Tau-induced rough eye, and perform a genetic screen of modifiers of Tau toxicity in the Drosophila eye." @default.
- W2565612004 created "2017-01-06" @default.
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- W2565612004 date "2016-12-15" @default.
- W2565612004 modified "2023-10-18" @default.
- W2565612004 title "Identification of Tau Toxicity Modifiers in the Drosophila Eye" @default.
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- W2565612004 doi "https://doi.org/10.1007/978-1-4939-6598-4_26" @default.
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