FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2565654865> ?p ?o ?g. }

• W2565654865 endingPage "e20623" @default.
• W2565654865 startingPage "e20623" @default.
• W2565654865 abstract "e20623 Background: Malignant spinal cord compression (MSCC) is a major oncological complication. The management of Impending Malignant Spinal Cord Compression (IMSCC) remains unclear. Radiotherapy (RT) is often the sole management of both entities. Our aim was to prospectively evaluate the functional outcome of MSCC and IMSCC. Methods: All pts with MSCC and IMSCC treated by RT in our institution were screened for 2 national trials (ICORG 05–03/07–11). Non-eligible pts were prospectively evaluated and followed with assessment of mobility (modified Tomita scale) and sphincter function (continence/ incontinence/catheter) at baseline and 5 weeks posttreatment. Results: From 08/07 to 11/08, 54 pts [23 IMSCC, 31 MSCC] were followed. 31 pts were male. The median age was 60.5 y (30–86). The primary tumours were haematological [13 pts], lung [10], prostate [8], renal cell [6] and breast [5]. 51 pts had diagnostic MRI. The compression level was cervical in 6 pts, thoracic in 27, lumbosacral in 16, and 5 had multiple levels. 2D RT was used with varying radiation schedules: 20Gy/5fractions (f) [32 pts], 30Gy/10f [12] and other [10]. At baseline, normal mobility was found in 29 pts, mildly impaired mobility in 15 and immobility in 10. 7 pts had sphincter dysfunction. At 5 weeks, 38 pts (16 IMSCC, 22 MSCC) were evaluable (37 for mobility score, 38 for sphincter function). 10 pts had died and 6 were lost to follow up. Overall mobility was stable, improved or worse in 28 pts, 3 pts and 6 pts respectively. The mobility score was worse in 4 pts with IMSCC and 2 pts with MSCC. Improvement of mobility score was seen in 2 pts with MSCC. Among the 7 pts with baseline sphincter dysfunction, 2 pts improved. New sphincter dysfunction after RT was seen in 2 pts with IMSCC. Conclusions: The functional outcome of MSCC treated by RT alone remains poor, with minimal mobility and sphincter improvement. Functional outcome of pts with IMSCC is worrying with a worsening of mobility and/or occurrence of sphincter dysfunction in a large number of patients. No significant financial relationships to disclose." @default.
• W2565654865 created "2017-01-06" @default.
• W2565654865 creator A5014093898 @default.
• W2565654865 creator A5016066980 @default.
• W2565654865 creator A5016824298 @default.
• W2565654865 creator A5045610877 @default.
• W2565654865 creator A5084910312 @default.
• W2565654865 creator A5089838549 @default.
• W2565654865 date "2009-05-20" @default.
• W2565654865 modified "2023-10-14" @default.
• W2565654865 title "Functional outcome of malignant spinal cord compression treated with radiotherapy alone: A prospective analysis" @default.
• W2565654865 doi "https://doi.org/10.1200/jco.2009.27.15_suppl.e20623" @default.
• W2565654865 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/27961600" @default.
• W2565654865 hasPublicationYear "2009" @default.
• W2565654865 type Work @default.
• W2565654865 sameAs 2565654865 @default.
• W2565654865 citedByCount "0" @default.
• W2565654865 crossrefType "journal-article" @default.
• W2565654865 hasAuthorship W2565654865A5014093898 @default.
• W2565654865 hasAuthorship W2565654865A5016066980 @default.
• W2565654865 hasAuthorship W2565654865A5016824298 @default.
• W2565654865 hasAuthorship W2565654865A5045610877 @default.
• W2565654865 hasAuthorship W2565654865A5084910312 @default.
• W2565654865 hasAuthorship W2565654865A5089838549 @default.
• W2565654865 hasConcept C118552586 @default.
• W2565654865 hasConcept C141071460 @default.
• W2565654865 hasConcept C2778231337 @default.
• W2565654865 hasConcept C2780775167 @default.
• W2565654865 hasConcept C2780877482 @default.
• W2565654865 hasConcept C509974204 @default.
• W2565654865 hasConcept C7146039 @default.
• W2565654865 hasConcept C71924100 @default.
• W2565654865 hasConceptScore W2565654865C118552586 @default.
• W2565654865 hasConceptScore W2565654865C141071460 @default.
• W2565654865 hasConceptScore W2565654865C2778231337 @default.
• W2565654865 hasConceptScore W2565654865C2780775167 @default.
• W2565654865 hasConceptScore W2565654865C2780877482 @default.
• W2565654865 hasConceptScore W2565654865C509974204 @default.
• W2565654865 hasConceptScore W2565654865C7146039 @default.
• W2565654865 hasConceptScore W2565654865C71924100 @default.
• W2565654865 hasIssue "15_suppl" @default.
• W2565654865 hasLocation W25656548651 @default.
• W2565654865 hasOpenAccess W2565654865 @default.
• W2565654865 hasPrimaryLocation W25656548651 @default.
• W2565654865 hasRelatedWork W1969293642 @default.
• W2565654865 hasRelatedWork W2002120878 @default.
• W2565654865 hasRelatedWork W2003938723 @default.
• W2565654865 hasRelatedWork W2021771973 @default.
• W2565654865 hasRelatedWork W2047967234 @default.
• W2565654865 hasRelatedWork W2118496982 @default.
• W2565654865 hasRelatedWork W2140167667 @default.
• W2565654865 hasRelatedWork W2348857921 @default.
• W2565654865 hasRelatedWork W2439875401 @default.
• W2565654865 hasRelatedWork W2977919527 @default.
• W2565654865 hasVolume "27" @default.
• W2565654865 isParatext "false" @default.
• W2565654865 isRetracted "false" @default.
• W2565654865 magId "2565654865" @default.
• W2565654865 workType "article" @default.