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- W2565771030 abstract "The oral cavity contains some of the most varied and vast flora in the entire human body and is the main entrance for 2 systems vital to human function and physiology, the gastrointestinal and respiratory systems. Several diseases involve these 2 systems and manifest in the oral cavity. In addition, a specific pathologic condition, such as periodontitis the human oral cavity is a complex biological system in which members of a microbial community interact with themselves as well as with different host structures and components Porphyromonas gingivalis, Streptococcus mutans and Treponema denticola cause periodontitis. The pathogenisis of this dental infection is a multi factorial process that results in a serious degenerative disease of the periodontium. Researchers have resulted in the identification of important virulence factors. These researches have provided a narrow picture of the steps of this complex process. In the present study Ferric binding protein is taken as a case study molecule to understand high reactive responses of various drugs administered for the oral periodontitis. The drugs are being compared with the Fbp. The Fbp interacted with doxycycline, flurbiprofen and chlorhexidine using docking methods." @default.
- W2565771030 created "2017-01-06" @default.
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- W2565771030 date "2014-04-21" @default.
- W2565771030 modified "2023-09-23" @default.
- W2565771030 title "Computational Analysis of Oral Disease (Periodontitis) for Drug Targets" @default.
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