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- W2566092685 abstract "Background: Leukocytes present in the airways play very crucial role in the manifestation of obstructive airway disease (OADs). Although some studies have evaluated associations between spirometric variables and sputum leukocyte profile in OADs, association between sputum leukocytes, lung volumes and airway conductance has not been studied extensively. Methods: Among 20 healthy (mean age 63.1±6.7 years), 19 asthmatics (56.4±13.5 years) and 29 patients with chronic obstructive pulmonary diseases (66.3±6.6 years), we measured lung volumes and capacities using spirometry and body plethysmography and quantified leukocytes from induced sputum. We compared the differences lung function variables and sputum cell counts using one-way analysis of variance (ANOVA) and also performed Pearson9s correlation to test the association between sputum leukocyte profile and lung function variables. Results: Specific airway conductance (sGaw) was found significantly reduced (p Conclusion: Poor airway conductance is an important pathophysiological condition in COPD and, which is manifested by increased infiltration of neutrophils in the airways." @default.
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- W2566092685 date "2015-09-01" @default.
- W2566092685 modified "2023-09-25" @default.
- W2566092685 title "Association between sputum cytology and lung function in patients with asthma and COPD" @default.
- W2566092685 doi "https://doi.org/10.1183/13993003.congress-2015.pa2266" @default.
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