FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2566392382> ?p ?o ?g. }

• W2566392382 abstract "Abstract Background: The global spread of carbapenem resistant Enterobacteriaceae (CRE) has limited the physicians’ antimicrobial treatment options of infected patients. CRE’s which carry the Klebsiella pneumonia Carbapenemase ( bla KPC ) resistance mechanism have been rapidly spreading in many parts of the world, and have been responsible for high patients’ morbidity and mortality. Methods: Two protocols recommended by the Center for Disease Control and Prevention (CDC) were followed to detect CRE’s in Palestine . In addition, the antimicrobial sensitivity patterns for several antibiotic classes were determined for the isolated CRE’s by the disc diffusion method according to the clinical and laboratory standard institute (CLSI) M100-S22 guidelines. The Minimal Inhibitory Concentrations (MICs) of the carbapenem, ertapenem, imipenem and meropenem were determined for all the CRE’s by E-test. The isolates β-lactam resistance mechanisms were further investigated by analyzing 31 different types of β–lactamase genes by polymerase chain reaction (PCR). Results: Four bacterial isolates, 3 Enterobacter cloacae and 1 Klebsiella pneumonia e, were determined to be non-susceptible to one or all of the carbapenems (ertapenem, imipenem and meropenem) tested. All isolates which carried the bla KPC-2 gene showed an extreme drug resistance profile. These isolates were resistant to all β-lactam antibiotics, co-trimoxazole and gentamicin, while susceptible to only amikacin and colistin sulfate. Different combination of plasmid encoded b –lactamase genes ( bla TEM , bla SHV , bla OXA-1 , bla MIR-1 , bla GES-23 and bla KPC-2 ) were present in these isolates. Of interest, was the isolation of the first E. cloacae strains co-producing the bla KPC-2 and a novel bla GES-23 β-lactamase. Conclusions: The presence of all these plasmid encoded b -lactamase in Palestine is alarming and mandates actions to be taken to control antibiotics usage and the activation of hospital infection control programs in order to prevent the spread of these extremely drug resistant bacteria." @default.
• W2566392382 created "2017-01-06" @default.
• W2566392382 creator A5001122825 @default.
• W2566392382 creator A5005237590 @default.
• W2566392382 creator A5009749627 @default.
• W2566392382 creator A5010928182 @default.
• W2566392382 creator A5020596537 @default.
• W2566392382 creator A5036291959 @default.
• W2566392382 creator A5039525410 @default.
• W2566392382 creator A5052232519 @default.
• W2566392382 creator A5063092319 @default.
• W2566392382 creator A5069951437 @default.
• W2566392382 creator A5070854627 @default.
• W2566392382 creator A5084177297 @default.
• W2566392382 creator A5090270986 @default.
• W2566392382 date "2012-08-10" @default.
• W2566392382 modified "2023-09-23" @default.
• W2566392382 title "Emergence of Klebsiella pneumoniae Carbapenemase (blaKPC-2) in members of the Enterobacteriaceae family in Palestine" @default.
• W2566392382 hasPublicationYear "2012" @default.
• W2566392382 type Work @default.
• W2566392382 sameAs 2566392382 @default.
• W2566392382 citedByCount "2" @default.
• W2566392382 countsByYear W25663923822013 @default.
• W2566392382 countsByYear W25663923822020 @default.
• W2566392382 crossrefType "journal-article" @default.
• W2566392382 hasAuthorship W2566392382A5001122825 @default.
• W2566392382 hasAuthorship W2566392382A5005237590 @default.
• W2566392382 hasAuthorship W2566392382A5009749627 @default.
• W2566392382 hasAuthorship W2566392382A5010928182 @default.
• W2566392382 hasAuthorship W2566392382A5020596537 @default.
• W2566392382 hasAuthorship W2566392382A5036291959 @default.
• W2566392382 hasAuthorship W2566392382A5039525410 @default.
• W2566392382 hasAuthorship W2566392382A5052232519 @default.
• W2566392382 hasAuthorship W2566392382A5063092319 @default.
• W2566392382 hasAuthorship W2566392382A5069951437 @default.
• W2566392382 hasAuthorship W2566392382A5070854627 @default.
• W2566392382 hasAuthorship W2566392382A5084177297 @default.
• W2566392382 hasAuthorship W2566392382A5090270986 @default.
• W2566392382 hasConcept C104317684 @default.
• W2566392382 hasConcept C2775992322 @default.
• W2566392382 hasConcept C2776124114 @default.
• W2566392382 hasConcept C2776685102 @default.
• W2566392382 hasConcept C2776933286 @default.
• W2566392382 hasConcept C2777058267 @default.
• W2566392382 hasConcept C2777402170 @default.
• W2566392382 hasConcept C2777427914 @default.
• W2566392382 hasConcept C2777637488 @default.
• W2566392382 hasConcept C2778368673 @default.
• W2566392382 hasConcept C2778910516 @default.
• W2566392382 hasConcept C2779259085 @default.
• W2566392382 hasConcept C2779375183 @default.
• W2566392382 hasConcept C2779489039 @default.
• W2566392382 hasConcept C2779631663 @default.
• W2566392382 hasConcept C4937899 @default.
• W2566392382 hasConcept C501593827 @default.
• W2566392382 hasConcept C523546767 @default.
• W2566392382 hasConcept C54355233 @default.
• W2566392382 hasConcept C547475151 @default.
• W2566392382 hasConcept C86803240 @default.
• W2566392382 hasConcept C89423630 @default.
• W2566392382 hasConcept C94665300 @default.
• W2566392382 hasConceptScore W2566392382C104317684 @default.
• W2566392382 hasConceptScore W2566392382C2775992322 @default.
• W2566392382 hasConceptScore W2566392382C2776124114 @default.
• W2566392382 hasConceptScore W2566392382C2776685102 @default.
• W2566392382 hasConceptScore W2566392382C2776933286 @default.
• W2566392382 hasConceptScore W2566392382C2777058267 @default.
• W2566392382 hasConceptScore W2566392382C2777402170 @default.
• W2566392382 hasConceptScore W2566392382C2777427914 @default.
• W2566392382 hasConceptScore W2566392382C2777637488 @default.
• W2566392382 hasConceptScore W2566392382C2778368673 @default.
• W2566392382 hasConceptScore W2566392382C2778910516 @default.
• W2566392382 hasConceptScore W2566392382C2779259085 @default.
• W2566392382 hasConceptScore W2566392382C2779375183 @default.
• W2566392382 hasConceptScore W2566392382C2779489039 @default.
• W2566392382 hasConceptScore W2566392382C2779631663 @default.
• W2566392382 hasConceptScore W2566392382C4937899 @default.
• W2566392382 hasConceptScore W2566392382C501593827 @default.
• W2566392382 hasConceptScore W2566392382C523546767 @default.
• W2566392382 hasConceptScore W2566392382C54355233 @default.
• W2566392382 hasConceptScore W2566392382C547475151 @default.
• W2566392382 hasConceptScore W2566392382C86803240 @default.
• W2566392382 hasConceptScore W2566392382C89423630 @default.
• W2566392382 hasConceptScore W2566392382C94665300 @default.
• W2566392382 hasIssue "2" @default.
• W2566392382 hasLocation W25663923821 @default.
• W2566392382 hasOpenAccess W2566392382 @default.
• W2566392382 hasPrimaryLocation W25663923821 @default.
• W2566392382 hasRelatedWork W1567348816 @default.
• W2566392382 hasRelatedWork W2009732714 @default.
• W2566392382 hasRelatedWork W2096585007 @default.
• W2566392382 hasRelatedWork W2112853072 @default.
• W2566392382 hasRelatedWork W2171201534 @default.
• W2566392382 hasRelatedWork W2491735233 @default.
• W2566392382 hasRelatedWork W2762519375 @default.
• W2566392382 hasRelatedWork W2797044067 @default.
• W2566392382 hasRelatedWork W2947897475 @default.
• W2566392382 hasRelatedWork W2973139756 @default.
• W2566392382 hasRelatedWork W2973696540 @default.
• W2566392382 hasRelatedWork W2990258313 @default.

• next