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- W2566996903 abstract "Hepatitis C Virus (HCV) infection is a major global disease which often leads to morbidity and mortality. Low survival is related to the lack of adequate diagnostic because HCV infection is frequently asymptomatic and there are no specific diagnostic tests due to the fast transformation of the virus. Here, we investigated the VLPs (virus-like particles) of HCV local isolate as an immunoassay diagnostic approach to detect HCV infection, especially in Indonesia. The core, E1, and E2 of HCV local isolate genes were cloned and molecular analyzed, either as single or in recombinant-VLP form, to determine the molecular and chemical characteristics of each VLPs related to their potential use as an immunoassay detection method for HCV infection. The results indicated the molecular and chemical character of each VLPs are comparable. Conclusion: VLPs of HCV has the potential as an immunoassay diagnostic approach to detect HCV infection." @default.
- W2566996903 created "2017-01-06" @default.
- W2566996903 creator A5007872627 @default.
- W2566996903 date "2017-01-01" @default.
- W2566996903 modified "2023-10-12" @default.
- W2566996903 title "VLPs of HCV local isolates for HCV immunoassay diagnostic approach in Indonesia" @default.
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- W2566996903 doi "https://doi.org/10.1063/1.4968353" @default.
- W2566996903 hasPublicationYear "2017" @default.
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