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• W2567151374 abstract "Background Hyperuricemia is known to be an independent risk factor for cardiovascular disease. The condition has been poorly researched in Sub-Saharan Africa and Ghana in particular.The aim of this study was to investigate the distribution of hyperuricaemia among metabolic conditions in a tertiary care center in Ghanaand the association of serum uric acid (SUA) with known demographic, anthropometric, and cardiovascular risk factors. Methods We designed a cross-sectional descriptive study comprising 372 subjects aged 20 years and above. Demographic and social data were obtained using a questionnaire. Anthropometric (height, weight, waist circumference) and blood pressure measurements were taken. Ten millilitres of venous blood samples were taken for SUA and other biochemistry investigations. Hyperuricaemia was defined as SUA  0.36 mmol/L in females and  0.42 mmol/L for males. Results One hundred and forty five men and 227 women participated in the study. The mean (SD) SUA level was 367.8 (110.2) µmol/L for men and 312.1 (108.8) µmol/L for women. The overall prevalence of hyperuricaemia was 29.8% (Males 30.3% vs. Females 29.5%, p = 0.87) .Measures of obesity, hypertension and diabetes were significant predictors of uric acid levels in univariate analyses. In multivariate linear regression analysis, after adjusting for age and sex, uric acid level was still associated with BMI (r=4.92, p<0.001) and SBP (r=0.89, p<0.01). Conclusions Obesity, diabetes mellitus and hypertension were all significant predictors of hyperuricaemia. These observations call for subsequent studies into the clinical importance of treating hyperuricaemia among patients with cardiovascular complications." @default.
• W2567151374 created "2017-01-06" @default.
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• W2567151374 date "2015-01-01" @default.
• W2567151374 modified "2023-09-27" @default.
• W2567151374 title "Factors Associated with Hyperuricaemia in a Tertiary Care Center in Ghana" @default.
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