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- W2567175034 abstract "Calorimetry is a valuable tool in pharmaceutical, biochemical and clinical diagnostic application areas. Thermodynamic quantities such as enthalpy of reaction are an indication of the efficacy of the interaction between active compounds. This information can enable acceleration of the drug development process by facilitating proper selection of the most promising compounds for later stages of development. A microfluidic calorimeter is being developed which offers reduced compound consumption, shorter experiment time, and higher throughput. The calorimeter employs a novel optical sensor based on the extraordinary optical transmission (EOT) of light through nanohole arrays (NHAs) which offers fine temperature and spatial resolution. Thermodynamic quantities such as enthalpy of reaction and binding constant can then be extracted from the temperature and concentration measurements." @default.
- W2567175034 created "2017-01-06" @default.
- W2567175034 creator A5005235427 @default.
- W2567175034 date "2021-05-10" @default.
- W2567175034 modified "2023-10-17" @default.
- W2567175034 title "CFD analysis of EDTA-CaCl2 reaction in a microfluidic channel to aid in design of novel calorimeter device" @default.
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- W2567175034 doi "https://doi.org/10.17760/d20213027" @default.
- W2567175034 hasPublicationYear "2021" @default.
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