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- W2567415105 abstract "Aims/Introduction Epidemiological evidence for the effect of omega-3 fatty acids on the risk of type 2 diabetes is controversial. A meta-analysis based on prospective cohorts was carried out to evaluate this issue. Materials and Methods Pooled diabetic risk was calculated using a fixed or random effects model. The dose–response relationship was assessed by meta-regression analysis. Results The study showed that consumption of single omega-3 was associated with an increased risk of type 2 diabetes (relative risk [RR] = 1.45, P < 0.001); whereas the RR for mixed omega-3 was statistically insignificant. The dose–response curve presented an inverted U-shape of diabetes risk corresponding to the dose of omega-3 consumption. Subanalysis showed that omega-3 was inversely associated with type 2 diabetes risk in Asians (RR = 0.82, P < 0.001); whereas the risk was increased in Westerners (RR = 1.30, P < 0.001). Studies with follow-up duration ≥16 years and baseline age ≥54 years showed a positive association between type 2 diabetes risk and omega-3 intake. Conclusions The present findings suggest that dosage and composition of omega-3, ethnicity, trial duration, and age could influence the effect of omega-3 on type 2 diabetes progression." @default.
- W2567415105 created "2017-01-06" @default.
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- W2567415105 date "2017-02-03" @default.
- W2567415105 modified "2023-09-29" @default.
- W2567415105 title "Association between omega-3 fatty acids consumption and the risk of type 2 diabetes: A meta-analysis of cohort studies" @default.
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- W2567415105 doi "https://doi.org/10.1111/jdi.12614" @default.
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