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- W2567503517 abstract "Abstract Many wildlife populations are declining at rates higher than can be explained by known threats to biodiversity. Recently, thiamine (vitamin B 1 ) deficiency has emerged as a possible contributing cause. Here, thiamine status was systematically investigated in three animal classes: bivalves, ray-finned fishes, and birds. Thiamine diphosphate is required as a cofactor in at least five life-sustaining enzymes that are required for basic cellular metabolism. Analysis of different phosphorylated forms of thiamine, as well as of activities and amount of holoenzyme and apoenzyme forms of thiamine-dependent enzymes, revealed episodically occurring thiamine deficiency in all three animal classes. These biochemical effects were also linked to secondary effects on growth, condition, liver size, blood chemistry and composition, histopathology, swimming behaviour and endurance, parasite infestation, and reproduction. It is unlikely that the thiamine deficiency is caused by impaired phosphorylation within the cells. Rather, the results point towards insufficient amounts of thiamine in the food. By investigating a large geographic area, by extending the focus from lethal to sublethal thiamine deficiency, and by linking biochemical alterations to secondary effects, we demonstrate that the problem of thiamine deficiency is considerably more widespread and severe than previously reported." @default.
- W2567503517 created "2017-01-06" @default.
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- W2567503517 date "2016-12-13" @default.
- W2567503517 modified "2023-09-30" @default.
- W2567503517 title "Widespread episodic thiamine deficiency in Northern Hemisphere wildlife" @default.
- W2567503517 cites W1483180640 @default.
- W2567503517 cites W1819342721 @default.
- W2567503517 cites W1856719834 @default.
- W2567503517 cites W1965939276 @default.
- W2567503517 cites W1976968605 @default.
- W2567503517 cites W1983584376 @default.
- W2567503517 cites W1988843930 @default.
- W2567503517 cites W1989294799 @default.
- W2567503517 cites W1992913491 @default.
- W2567503517 cites W1993679589 @default.
- W2567503517 cites W1994707943 @default.
- W2567503517 cites W2002682820 @default.
- W2567503517 cites W2002724074 @default.
- W2567503517 cites W2005368251 @default.
- W2567503517 cites W2010614057 @default.
- W2567503517 cites W2014009906 @default.
- W2567503517 cites W2014739701 @default.
- W2567503517 cites W2018200842 @default.
- W2567503517 cites W2025113427 @default.
- W2567503517 cites W2026219012 @default.
- W2567503517 cites W2033368618 @default.
- W2567503517 cites W2033839946 @default.
- W2567503517 cites W2035878224 @default.
- W2567503517 cites W2041344751 @default.
- W2567503517 cites W2050834877 @default.
- W2567503517 cites W2054057278 @default.
- W2567503517 cites W2056726738 @default.
- W2567503517 cites W2062467266 @default.
- W2567503517 cites W2064172252 @default.
- W2567503517 cites W2065150434 @default.
- W2567503517 cites W2066953299 @default.
- W2567503517 cites W2082593530 @default.
- W2567503517 cites W2084038253 @default.
- W2567503517 cites W2085178820 @default.
- W2567503517 cites W2087372525 @default.
- W2567503517 cites W2087582044 @default.
- W2567503517 cites W2088643277 @default.
- W2567503517 cites W2089840436 @default.
- W2567503517 cites W2090181122 @default.
- W2567503517 cites W2095533502 @default.
- W2567503517 cites W2096885696 @default.
- W2567503517 cites W2100936288 @default.
- W2567503517 cites W2105142632 @default.
- W2567503517 cites W2105755437 @default.
- W2567503517 cites W2110785824 @default.
- W2567503517 cites W2111307528 @default.
- W2567503517 cites W2111760270 @default.
- W2567503517 cites W2128356338 @default.
- W2567503517 cites W2134585782 @default.
- W2567503517 cites W2135940858 @default.
- W2567503517 cites W2136468831 @default.
- W2567503517 cites W2137011837 @default.
- W2567503517 cites W2140355147 @default.
- W2567503517 cites W2142500960 @default.
- W2567503517 cites W2143727454 @default.
- W2567503517 cites W2144671795 @default.
- W2567503517 cites W2157318354 @default.
- W2567503517 cites W2157691237 @default.
- W2567503517 cites W2160881014 @default.
- W2567503517 cites W2165593978 @default.
- W2567503517 cites W2167241330 @default.
- W2567503517 cites W2168020376 @default.
- W2567503517 cites W2171381662 @default.
- W2567503517 cites W2257855177 @default.
- W2567503517 cites W2268479893 @default.
- W2567503517 cites W2300689805 @default.
- W2567503517 cites W2313824839 @default.
- W2567503517 cites W2322806917 @default.
- W2567503517 cites W2346147944 @default.
- W2567503517 cites W2410617486 @default.
- W2567503517 cites W2422242742 @default.
- W2567503517 cites W2805008985 @default.
- W2567503517 cites W2992777935 @default.
- W2567503517 cites W3023071800 @default.