Matches in SemOpenAlex for { <https://semopenalex.org/work/W2567565954> ?p ?o ?g. }
Showing items 1 to 91 of
91
with 100 items per page.
- W2567565954 endingPage "399" @default.
- W2567565954 startingPage "394" @default.
- W2567565954 abstract "Previous studies comparing Clostridium difficile infection (CDI) due to different ribotypes have been conflicting, and many have only compared small numbers of cases or few ribotypes.To compare patient and episode characteristics for CDI due to different ribotypes.The ribotyping results from 3333 toxin-producing isolates collected from 110 Belgian hospitals between October 2010 and December 2015 were matched to clinical data from the national CDI surveillance database. Data for ribotypes with at least 100 occurrences were compared. In addition, the national reference laboratory quantitatively measured the level of toxin production in five randomly chosen cultured isolates for each of the most common ribotypes.Ribotypes with more than 100 occurrences were R014, R020, R002, R078, R027, R005 and R106 (Brazier classification). The median age for all patients was 79 years [patients with R027, 83 years (P<0.001); patients with R106, 73 years (P<0.001)]. In total, 10% of episodes were recurrences; values were higher for R027 (22%) and R106 (18%). CDI due to R078 was not significantly more likely to be community associated than healthcare associated (28% vs 24%; P=0.1). Complications occurred in 7% of all episodes, and 12% for those with R027 and R078. However, after adjusting for age, onset outside the hospital and recurrence, R027 was no longer associated with complications [odds ratio (OR) 1.3, 95% confidence interval (CI) 0.7-2.4], unlike R078 (OR 1.7, 95% CI 1.0-2.6; P=0.04). A positive stool toxin test and greater levels of toxin production in the cultured isolates were more likely for R078 and R027.Out of the seven most common ribotypes in hospital patients, R078 and R027 were associated with higher rates of complications. Infections with R027 and R106 were more likely to be recurrent. The presence of toxin in stools was most likely with R078, R027 and R106, with highest levels of toxin production in vitro for R078 and R027. R060 produced the lowest levels of toxin in vitro." @default.
- W2567565954 created "2017-01-06" @default.
- W2567565954 creator A5007246828 @default.
- W2567565954 creator A5023705767 @default.
- W2567565954 creator A5054000066 @default.
- W2567565954 creator A5085193551 @default.
- W2567565954 date "2017-04-01" @default.
- W2567565954 modified "2023-09-24" @default.
- W2567565954 title "Clinical and laboratory features of the most common Clostridium difficile ribotypes isolated in Belgium" @default.
- W2567565954 cites W1966754565 @default.
- W2567565954 cites W2059182762 @default.
- W2567565954 cites W2061770273 @default.
- W2567565954 cites W2063214527 @default.
- W2567565954 cites W2068619078 @default.
- W2567565954 cites W2069027256 @default.
- W2567565954 cites W2070480983 @default.
- W2567565954 cites W2077265045 @default.
- W2567565954 cites W2100938352 @default.
- W2567565954 cites W2114318563 @default.
- W2567565954 cites W2115999384 @default.
- W2567565954 cites W2124462639 @default.
- W2567565954 cites W2137726039 @default.
- W2567565954 cites W2165833212 @default.
- W2567565954 doi "https://doi.org/10.1016/j.jhin.2016.12.011" @default.
- W2567565954 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/28153559" @default.
- W2567565954 hasPublicationYear "2017" @default.
- W2567565954 type Work @default.
- W2567565954 sameAs 2567565954 @default.
- W2567565954 citedByCount "9" @default.
- W2567565954 countsByYear W25675659542017 @default.
- W2567565954 countsByYear W25675659542018 @default.
- W2567565954 countsByYear W25675659542020 @default.
- W2567565954 countsByYear W25675659542022 @default.
- W2567565954 countsByYear W25675659542023 @default.
- W2567565954 crossrefType "journal-article" @default.
- W2567565954 hasAuthorship W2567565954A5007246828 @default.
- W2567565954 hasAuthorship W2567565954A5023705767 @default.
- W2567565954 hasAuthorship W2567565954A5054000066 @default.
- W2567565954 hasAuthorship W2567565954A5085193551 @default.
- W2567565954 hasConcept C104317684 @default.
- W2567565954 hasConcept C126322002 @default.
- W2567565954 hasConcept C156957248 @default.
- W2567565954 hasConcept C2777367657 @default.
- W2567565954 hasConcept C2777368272 @default.
- W2567565954 hasConcept C2994496256 @default.
- W2567565954 hasConcept C44249647 @default.
- W2567565954 hasConcept C49105822 @default.
- W2567565954 hasConcept C501593827 @default.
- W2567565954 hasConcept C54355233 @default.
- W2567565954 hasConcept C71924100 @default.
- W2567565954 hasConcept C86803240 @default.
- W2567565954 hasConcept C89423630 @default.
- W2567565954 hasConcept C90924648 @default.
- W2567565954 hasConcept C97505648 @default.
- W2567565954 hasConceptScore W2567565954C104317684 @default.
- W2567565954 hasConceptScore W2567565954C126322002 @default.
- W2567565954 hasConceptScore W2567565954C156957248 @default.
- W2567565954 hasConceptScore W2567565954C2777367657 @default.
- W2567565954 hasConceptScore W2567565954C2777368272 @default.
- W2567565954 hasConceptScore W2567565954C2994496256 @default.
- W2567565954 hasConceptScore W2567565954C44249647 @default.
- W2567565954 hasConceptScore W2567565954C49105822 @default.
- W2567565954 hasConceptScore W2567565954C501593827 @default.
- W2567565954 hasConceptScore W2567565954C54355233 @default.
- W2567565954 hasConceptScore W2567565954C71924100 @default.
- W2567565954 hasConceptScore W2567565954C86803240 @default.
- W2567565954 hasConceptScore W2567565954C89423630 @default.
- W2567565954 hasConceptScore W2567565954C90924648 @default.
- W2567565954 hasConceptScore W2567565954C97505648 @default.
- W2567565954 hasIssue "4" @default.
- W2567565954 hasLocation W25675659541 @default.
- W2567565954 hasLocation W25675659542 @default.
- W2567565954 hasOpenAccess W2567565954 @default.
- W2567565954 hasPrimaryLocation W25675659541 @default.
- W2567565954 hasRelatedWork W1898462148 @default.
- W2567565954 hasRelatedWork W2080594197 @default.
- W2567565954 hasRelatedWork W2103010883 @default.
- W2567565954 hasRelatedWork W2132207617 @default.
- W2567565954 hasRelatedWork W2150489142 @default.
- W2567565954 hasRelatedWork W2405583998 @default.
- W2567565954 hasRelatedWork W2409275213 @default.
- W2567565954 hasRelatedWork W2416013247 @default.
- W2567565954 hasRelatedWork W2442738383 @default.
- W2567565954 hasRelatedWork W2968050891 @default.
- W2567565954 hasVolume "95" @default.
- W2567565954 isParatext "false" @default.
- W2567565954 isRetracted "false" @default.
- W2567565954 magId "2567565954" @default.
- W2567565954 workType "article" @default.