Matches in SemOpenAlex for { <https://semopenalex.org/work/W2567903504> ?p ?o ?g. }
- W2567903504 endingPage "17" @default.
- W2567903504 startingPage "1" @default.
- W2567903504 abstract "Articular cartilage injury and defect caused by trauma and chronic osteoarthritis vascularity are very common, while the repair of injured cartilage remains a great challenge due to its limited healing capacity. Stem cell-based tissue engineering provides a promising treatment option for injured articular cartilage because of the cells potential for multiple differentiations. However, its application has been largely limited by stem cell type, number, source, proliferation, and differentiation. We hypothesized that (1) adipose-derived stem cells are ideal seed cells for articular cartilage repair because of their accessibility and abundance and (2) the microenvironment of articular cartilage could induce adipose-derived stem cells (ADSCs) to differentiate into chondrocytes. In order to test our hypotheses, we isolated stem cells from rabbit adipose tissues and cocultured these ADSCs with rabbit articular cartilage chondrocytes. We found that when ADSCs were cocultured with chondrocytes, the proliferation of articular cartilage chondrocytes was promoted, the apoptosis of chondrocytes was inhibited, and the osteogenic and chondrogenic differentiation of ADSCs was enhanced. The study on the mechanism of this coculture system indicated that the role of this coculture system is similar to the function of TGF- β 1 in the promotion of chondrocytes." @default.
- W2567903504 created "2017-01-13" @default.
- W2567903504 creator A5007126580 @default.
- W2567903504 creator A5020944550 @default.
- W2567903504 creator A5040747953 @default.
- W2567903504 creator A5053825518 @default.
- W2567903504 creator A5065032339 @default.
- W2567903504 creator A5068295256 @default.
- W2567903504 creator A5086706882 @default.
- W2567903504 date "2017-01-01" @default.
- W2567903504 modified "2023-10-15" @default.
- W2567903504 title "Adipose-Derived Stem Cells Cocultured with Chondrocytes Promote the Proliferation of Chondrocytes" @default.
- W2567903504 cites W1197465675 @default.
- W2567903504 cites W1883403040 @default.
- W2567903504 cites W1926810203 @default.
- W2567903504 cites W1984095256 @default.
- W2567903504 cites W1994876269 @default.
- W2567903504 cites W2001958765 @default.
- W2567903504 cites W2013839360 @default.
- W2567903504 cites W2013964647 @default.
- W2567903504 cites W2016044878 @default.
- W2567903504 cites W2022228053 @default.
- W2567903504 cites W2022630144 @default.
- W2567903504 cites W2037945544 @default.
- W2567903504 cites W2098345480 @default.
- W2567903504 cites W2105812958 @default.
- W2567903504 cites W2111019735 @default.
- W2567903504 cites W2128555837 @default.
- W2567903504 cites W2164962083 @default.
- W2567903504 cites W2167527822 @default.
- W2567903504 cites W2173339837 @default.
- W2567903504 cites W2173497140 @default.
- W2567903504 cites W2175915881 @default.
- W2567903504 cites W2193828245 @default.
- W2567903504 cites W2204953460 @default.
- W2567903504 cites W2214981143 @default.
- W2567903504 cites W2222717482 @default.
- W2567903504 cites W2267206565 @default.
- W2567903504 cites W2296380648 @default.
- W2567903504 cites W2302693978 @default.
- W2567903504 cites W2303185963 @default.
- W2567903504 cites W2313491747 @default.
- W2567903504 cites W2322339110 @default.
- W2567903504 cites W2472692592 @default.
- W2567903504 cites W2597632520 @default.
- W2567903504 cites W2605187236 @default.
- W2567903504 doi "https://doi.org/10.1155/2017/1709582" @default.
- W2567903504 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/5241498" @default.
- W2567903504 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/28133485" @default.
- W2567903504 hasPublicationYear "2017" @default.
- W2567903504 type Work @default.
- W2567903504 sameAs 2567903504 @default.
- W2567903504 citedByCount "26" @default.
- W2567903504 countsByYear W25679035042017 @default.
- W2567903504 countsByYear W25679035042018 @default.
- W2567903504 countsByYear W25679035042019 @default.
- W2567903504 countsByYear W25679035042020 @default.
- W2567903504 countsByYear W25679035042021 @default.
- W2567903504 countsByYear W25679035042022 @default.
- W2567903504 countsByYear W25679035042023 @default.
- W2567903504 crossrefType "journal-article" @default.
- W2567903504 hasAuthorship W2567903504A5007126580 @default.
- W2567903504 hasAuthorship W2567903504A5020944550 @default.
- W2567903504 hasAuthorship W2567903504A5040747953 @default.
- W2567903504 hasAuthorship W2567903504A5053825518 @default.
- W2567903504 hasAuthorship W2567903504A5065032339 @default.
- W2567903504 hasAuthorship W2567903504A5068295256 @default.
- W2567903504 hasAuthorship W2567903504A5086706882 @default.
- W2567903504 hasBestOaLocation W25679035041 @default.
- W2567903504 hasConcept C105702510 @default.
- W2567903504 hasConcept C123012128 @default.
- W2567903504 hasConcept C126322002 @default.
- W2567903504 hasConcept C13685319 @default.
- W2567903504 hasConcept C142724271 @default.
- W2567903504 hasConcept C171089720 @default.
- W2567903504 hasConcept C185592680 @default.
- W2567903504 hasConcept C202751555 @default.
- W2567903504 hasConcept C204787440 @default.
- W2567903504 hasConcept C20875687 @default.
- W2567903504 hasConcept C2776164576 @default.
- W2567903504 hasConcept C2777564180 @default.
- W2567903504 hasConcept C2780550940 @default.
- W2567903504 hasConcept C2781403057 @default.
- W2567903504 hasConcept C28328180 @default.
- W2567903504 hasConcept C3020332539 @default.
- W2567903504 hasConcept C35496256 @default.
- W2567903504 hasConcept C55493867 @default.
- W2567903504 hasConcept C71924100 @default.
- W2567903504 hasConcept C86803240 @default.
- W2567903504 hasConcept C95444343 @default.
- W2567903504 hasConceptScore W2567903504C105702510 @default.
- W2567903504 hasConceptScore W2567903504C123012128 @default.
- W2567903504 hasConceptScore W2567903504C126322002 @default.
- W2567903504 hasConceptScore W2567903504C13685319 @default.
- W2567903504 hasConceptScore W2567903504C142724271 @default.
- W2567903504 hasConceptScore W2567903504C171089720 @default.
- W2567903504 hasConceptScore W2567903504C185592680 @default.
- W2567903504 hasConceptScore W2567903504C202751555 @default.