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- W2568179911 abstract "In recent years, discovery of the cannabinoid receptors in the ocular tissues has opened up the possible utility of tetrahydrocannabinol (THC) and other cannabinoids in the management of several ocular diseases and conditions. The biopharmaceutical characteristics of THC, however, do not favor transmembrane diffusion. Additional physiological barriers, atypical of ocular drug delivery, makes THC delivery to the ocular tissues through the topical route even more challenging. Thus, careful formulation design and consideration is needed to translate the potential of THC into the preclinical and clinical settings. This chapter reviews some of the ocular conditions that can be impacted by THC, and the barriers to its delivery through the topical route. Strategies to improve ocular penetration of THC have also been discussed." @default.
- W2568179911 created "2017-01-13" @default.
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- W2568179911 date "2017-01-01" @default.
- W2568179911 modified "2023-09-25" @default.
- W2568179911 title "Ocular Delivery of Tetrahydrocannabinol" @default.
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- W2568179911 doi "https://doi.org/10.1016/b978-0-12-800756-3.00089-2" @default.
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