FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2568488308> ?p ?o ?g. }

• W2568488308 endingPage "34" @default.
• W2568488308 startingPage "22" @default.
• W2568488308 abstract "Intrahepatic cholangiocarcinoma (iCC) is a primary carcinoma of the liver with increasing significance and major pathogenic, clinical and therapeutic challenges. Classically, it arises from malignant transformation of cholangiocytes bordering small portal bile duct (BD) to second-order segmental large BDs. It has three major macroscopic growth pattern [mass-forming (MF), periductal infiltrative (PI), and intraductal growth (IG)] and histologically is a desmoplastic stroma-rich adenocarcinoma with cholangiocyte differentiation. Recent data pointed out noteworthy degree of heterogeneity in regards of their epidemiology and risk factors, pathological and molecular features, pathogenesis, clinical behaviors and treatment. Notably, several histological variants are described and can coexist within the same tumor. Several different cells of origin have also been depicted in a fraction of iCCs, amongst which malignant transformation of ductules, of hepatic stem/progenitor cells, of periductal glands or through oncogenic reprogramming of adult hepatocytes. A degree of pathological overlap with hepatocellular carcinoma (HCC) may be observed in a portion of iCC. A series of precursor lesions are today characterized and emphasize the existence of a multistep carcinogenesis process. Overall, these new data have brought up in proposal of new histological or molecular classifications, which could soon replace current anatomic-based classification and could have major impact on establishment of prognosis and on development of novel target treatment approaches." @default.
• W2568488308 created "2017-01-13" @default.
• W2568488308 creator A5063921293 @default.
• W2568488308 creator A5066096562 @default.
• W2568488308 creator A5073307450 @default.
• W2568488308 date "2017-02-01" @default.
• W2568488308 modified "2023-10-18" @default.
• W2568488308 title "Pathology of intrahepatic cholangiocarcinoma" @default.
• W2568488308 cites W1514468074 @default.
• W2568488308 cites W1741750461 @default.
• W2568488308 cites W1807442454 @default.
• W2568488308 cites W1841263046 @default.
• W2568488308 cites W1979566969 @default.
• W2568488308 cites W1995706631 @default.
• W2568488308 cites W2001820640 @default.
• W2568488308 cites W2002956764 @default.
• W2568488308 cites W2010416662 @default.
• W2568488308 cites W2011889329 @default.
• W2568488308 cites W2022823213 @default.
• W2568488308 cites W2033986568 @default.
• W2568488308 cites W2037873075 @default.
• W2568488308 cites W2043948917 @default.
• W2568488308 cites W2050826702 @default.
• W2568488308 cites W2052203960 @default.
• W2568488308 cites W2056132675 @default.
• W2568488308 cites W2058243348 @default.
• W2568488308 cites W2059634098 @default.
• W2568488308 cites W2063506633 @default.
• W2568488308 cites W2069947396 @default.
• W2568488308 cites W2071776374 @default.
• W2568488308 cites W2074833771 @default.
• W2568488308 cites W2080241245 @default.
• W2568488308 cites W2085195669 @default.
• W2568488308 cites W2090485181 @default.
• W2568488308 cites W2090907562 @default.
• W2568488308 cites W2092133163 @default.
• W2568488308 cites W2097063557 @default.
• W2568488308 cites W2107677923 @default.
• W2568488308 cites W2121456131 @default.
• W2568488308 cites W2145593859 @default.
• W2568488308 cites W2161610964 @default.
• W2568488308 cites W2164424438 @default.
• W2568488308 cites W2171708144 @default.
• W2568488308 cites W2193165261 @default.
• W2568488308 cites W2269996830 @default.
• W2568488308 cites W2282642897 @default.
• W2568488308 cites W2292031615 @default.
• W2568488308 cites W2300335242 @default.
• W2568488308 cites W2520593853 @default.
• W2568488308 cites W3562637 @default.
• W2568488308 cites W71106588 @default.
• W2568488308 doi "https://doi.org/10.21037/hbsn.2016.11.04" @default.
• W2568488308 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/5332210" @default.
• W2568488308 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/28261592" @default.
• W2568488308 hasPublicationYear "2017" @default.
• W2568488308 type Work @default.
• W2568488308 sameAs 2568488308 @default.
• W2568488308 citedByCount "75" @default.
• W2568488308 countsByYear W25684883082017 @default.
• W2568488308 countsByYear W25684883082018 @default.
• W2568488308 countsByYear W25684883082019 @default.
• W2568488308 countsByYear W25684883082020 @default.
• W2568488308 countsByYear W25684883082021 @default.
• W2568488308 countsByYear W25684883082022 @default.
• W2568488308 countsByYear W25684883082023 @default.
• W2568488308 crossrefType "journal-article" @default.
• W2568488308 hasAuthorship W2568488308A5063921293 @default.
• W2568488308 hasAuthorship W2568488308A5066096562 @default.
• W2568488308 hasAuthorship W2568488308A5073307450 @default.
• W2568488308 hasBestOaLocation W25684883082 @default.
• W2568488308 hasConcept C121608353 @default.
• W2568488308 hasConcept C126322002 @default.
• W2568488308 hasConcept C142724271 @default.
• W2568488308 hasConcept C201750760 @default.
• W2568488308 hasConcept C204232928 @default.
• W2568488308 hasConcept C207886595 @default.
• W2568488308 hasConcept C2778019345 @default.
• W2568488308 hasConcept C2779777945 @default.
• W2568488308 hasConcept C2780186670 @default.
• W2568488308 hasConcept C2780788601 @default.
• W2568488308 hasConcept C2780942790 @default.
• W2568488308 hasConcept C2781182431 @default.
• W2568488308 hasConcept C28328180 @default.
• W2568488308 hasConcept C2909135397 @default.
• W2568488308 hasConcept C31033888 @default.
• W2568488308 hasConcept C502942594 @default.
• W2568488308 hasConcept C52124034 @default.
• W2568488308 hasConcept C54355233 @default.
• W2568488308 hasConcept C555283112 @default.
• W2568488308 hasConcept C71924100 @default.
• W2568488308 hasConcept C86803240 @default.
• W2568488308 hasConceptScore W2568488308C121608353 @default.
• W2568488308 hasConceptScore W2568488308C126322002 @default.
• W2568488308 hasConceptScore W2568488308C142724271 @default.
• W2568488308 hasConceptScore W2568488308C201750760 @default.
• W2568488308 hasConceptScore W2568488308C204232928 @default.
• W2568488308 hasConceptScore W2568488308C207886595 @default.
• W2568488308 hasConceptScore W2568488308C2778019345 @default.

• next